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Research Output 2001 2019

  • 381 Citations
  • 11 h-Index
  • 36 Article
  • 3 Chapter
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Article
2019

Aeromonas sobria serine protease decreases epithelial Barrier function in T84 cells and accelerates bacterial translocation across the T84 monolayer in vitro

Kobayashi, H., Seike, S., Yamaguchi, M., Ueda, M., Takahashi, E., Okamoto, K. & Yamanaka, H., Jan 1 2019, In : PloS one. 14, 8, e0221344.

Research output: Contribution to journalArticle

Open Access
Aeromonas sobria
Bacterial Translocation
Aeromonas
Serine Proteases
serine proteinases

Chloroethylating anticancer drug-induced mutagenesis and its repair in Escherichia coli

Yamada, Y., Watanabe, S., Okamoto, K., Arimoto, S., Takahashi, E., Negishi, K. & Negishi, T., Apr 5 2019, In : Genes and Environment. 41, 1, 11.

Research output: Contribution to journalArticle

Open Access
Nimustine
Mutagenesis
DNA Repair
Carmustine
repair
1 Citation (Scopus)

Emergence of Azithromycin Resistance Mediated by Phosphotransferase-Encoding mph(A) in Diarrheagenic Vibrio fluvialis

Chowdhury, G., Ramamurthy, T., Ghosh, A., Dutta, S., Takahashi, E. & Mukhopadhyay, A. K., Jun 12 2019, In : mSphere. 4, 3

Research output: Contribution to journalArticle

Open Access
Azithromycin
Vibrio
Phosphotransferases
Genes
India
2017
2 Citations (Scopus)

E. coli mismatch repair enhances AT-to-GC mutagenesis caused by alkylating agents

Nakano, K., Yamada, Y., Takahashi, E., Arimoto, S., Okamoto, K., Negishi, K. & Negishi, T., Mar 1 2017, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 815, p. 22-27 6 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Alkylating Agents
Mutagenesis
Escherichia coli
Mutation
3 Citations (Scopus)

Involvement of the Arg566 residue of Aeromonas sobria serine protease in substrate specificity

Kobayashi, H., Otsubo, T., Teraoka, F., Ikeda, K., Seike, S., Takahashi, E., Okamoto, K., Yoshida, T., Tsuge, H. & Yamanaka, H., Oct 1 2017, In : PLoS One. 12, 10, e0186392.

Research output: Contribution to journalArticle

Aeromonas sobria
Aeromonas
Serine Proteases
serine proteinases
substrate specificity
2016
3 Citations (Scopus)
Aeromonas
Hemolysin Proteins
Staphylococcus aureus
Hemolysis
Bacteria
2014

Effects of oral administration of non-genotoxic hepato-hypertrophic compounds on metabolic potency of rat liver

Fang, X., Nunoshiba, T., Yoshida, M., Nishikawa, A., Nemoto, K., Degawa, M., Arimoto, S., Okamoto, K., Takahashi, E. & Negishi, T., 2014, In : Genes and Environment. 36, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Oral Administration
decabromobiphenyl ether
enzyme
mutagenicity
Dimethylnitrosamine
11 Citations (Scopus)

Properties of hemolysin and protease produced by Aeromonas trota

Takahashi, E., Ozaki, H., Fujii, Y., Kobayashi, H., Yamanaka, H., Arimoto, S., Negishi, T. & Okamoto, K., Mar 14 2014, In : PLoS One. 9, 3, e91149.

Research output: Contribution to journalArticle

Aeromonas trota
Aeromonas
Hemolysin Proteins
hemolysins
Peptide Hydrolases
2013
4 Citations (Scopus)

Analysis of carboxy terminal domain of metalloprotease of elastolytic Aeromonas hydrophila

Takahashi, E., Kobayashi, H., Yamanaka, H., Nakanishi, M., Tateishi, A., Abe, T., Arimoto, S., Negishi, T. & Okamoto, K., Jul 2013, In : Biological and Pharmaceutical Bulletin. 36, 7, p. 1174-1182 9 p.

Research output: Contribution to journalArticle

Aeromonas hydrophila
Metalloproteases
Adenosine Monophosphate
Elastin
Amino Acids
6 Citations (Scopus)

Distinct pathways for repairing mutagenic lesions induced by methylating and ethylating agents

Taira, K., Kaneto, S., Nakano, K., Watanabe, S., Takahashi, E., Arimoto, S., Okamoto, K., Schaaper, R. M., Negishi, K. & Negishi, T., May 2013, In : Mutagenesis. 28, 3, p. 341-350 10 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Repair
DNA Repair
Alkylation
Mutagenesis

Spermidine-analogous triamines suppressed the growth of candida albicans

Takahashi, E., Oono, S., Yamamoto, S., Arimoto, S., Negishi, T. & Okamoto, K., Sep 2013, In : Biological and Pharmaceutical Bulletin. 36, 9, p. 1440-1447 8 p.

Research output: Contribution to journalArticle

Spermidine
Candida albicans
Polyamines
Enzyme Inhibitors
Growth
2012
15 Citations (Scopus)

Development of a sensitive rRNA-targeted reverse transcription-quantitative polymerase chain reaction for detection of Vibrio cholerae/mimicus, V. parahaemolyticus/alginolyticus and Campylobacter jejuni/coli

Kurakawa, T., Kubota, H., Tsuji, H., Matsuda, K., Asahara, T., Takahashi, T., Ramamurthy, T., Hamabata, T., Takahashi, E., Miyoshi, S., Okamoto, K., Mukhopadhyay, A. K., Takeda, Y. & Nomoto, K., Jan 2012, In : Microbiology and Immunology. 56, 1, p. 10-20 11 p.

Research output: Contribution to journalArticle

Vibrio mimicus
Campylobacter coli
Campylobacter jejuni
Vibrio cholerae
Reverse Transcription
7 Citations (Scopus)

Hydrolysable tannins isolated from Syzygium aromaticum: Structure of a new C-Glucosidic ellagitannin and spectral features of tannins with a tergalloyl group

Bao, L. M., Eerdunbayaer, Nozaki, A., Takahashi, E., Okamoto, K., Ito, H. & Hatano, T., Jan 30 2012, In : Heterocycles. 85, 2, p. 365-381 17 p.

Research output: Contribution to journalArticle

Hydrolyzable Tannins
Syzygium
Gallic Acid
Tannins
Glucosides
1 Citation (Scopus)

Novel antimutagenic proteins in the edible mushroom Agrocybe cylindracea

Yoneda, K., Shiozawa, A., Kitahara, A., Takahashi, E., Arimoto, S., Okamoto, K. & Negishi, T., 2012, In : Genes and Environment. 34, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

Agrocybe
Agaricales
mushroom
Ammonium Sulfate
ammonium sulfate

Production and properties of lipase of Aeromonas sobria

Takahashi, E., Ito, H., Kobayashi, H., Yamanaka, H., Takeda, Y., Balakrish Nair, G., Arimoto, S., Negishi, T. & Okamoto, K., May 2012, In : Microbiology and Immunology. 56, 5, p. 295-307 13 p.

Research output: Contribution to journalArticle

Aeromonas
Lipase
Seawater
Genes
Proteins
2011
5 Citations (Scopus)

Inhibition of biosynthesis of metalloprotease of Aeromonas sobria by sodium chloride in the medium

Takahashi, E., Kobayashi, H., Yamanaka, H., Nair, G. B., Takeda, Y., Arimoto, S., Negishi, T. & Okamoto, K., Jan 2011, In : Microbiology and Immunology. 55, 1, p. 60-65 6 p.

Research output: Contribution to journalArticle

Aeromonas
Metalloproteases
Adenosine Monophosphate
Sodium Chloride
Serine Proteases
2010
6 Citations (Scopus)

Antifungal activity of essential oils and their constituents against Candida Spp. and their effects on activity of amphotericin B

Nozaki, A., Takahashi, E., Okamoto, K., Hideyuki, I. T. O. & Hatano, T., Jun 2010, In : Yakugaku Zasshi. 130, 6, p. 895-902 8 p.

Research output: Contribution to journalArticle

Amphotericin B
Volatile Oils
Candida
Clove Oil
Eugenol
8 Citations (Scopus)

Maturation pathway of metalloprotease produced by Aeromonas sobria

Takahashi, E., Fujii, Y., Kobayashi, H., Yamanaka, H., Nair, G. B., Takeda, Y., Arimoto, S., Negishi, T. & Okamoto, K., Oct 2010, In : Microbiology and Immunology. 54, 10, p. 596-605 10 p.

Research output: Contribution to journalArticle

Aeromonas
Metalloproteases
Serine Proteases
Adenosine Monophosphate
Nucleic Acid Databases
2009
5 Citations (Scopus)

The carboxy-terminal tail of Aeromonas sobria serine protease is associated with the chaperone

Kobayashi, H., Tateishi, A., Tsuge, H., Takahashi, E., Okamoto, K. & Yamanaka, H., Dec 2009, In : Microbiology and Immunology. 53, 12, p. 647-657 11 p.

Research output: Contribution to journalArticle

Aeromonas
Serine Proteases
Histidine
Tail
Periplasm
2008
3 Citations (Scopus)

Antibacterial effects of guava tannins and related polyphenols on Vibrio and Aeromonas species

Yamanaka, F., Hatano, T., Ito, H., Taniguchi, S., Takahashi, E. & Okamoto, K., 2008, In : Natural Product Communications. 3, 5, p. 711-720 10 p.

Research output: Contribution to journalArticle

Psidium
Aeromonas
Vibrio
guavas
Tannins
22 Citations (Scopus)

Design and synthesis of benzenesulfonanilides active against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus

Namba, K., Zheng, X., Motoshima, K., Kobayashi, H., Tai, A., Takahashi, E., Sasaki, K., Okamoto, K. & Kakuta, H., Jun 1 2008, In : Bioorganic and Medicinal Chemistry. 16, 11, p. 6131-6144 14 p.

Research output: Contribution to journalArticle

Methicillin
Vancomycin
Methicillin-Resistant Staphylococcus aureus
Dihydropteroate Synthase
Folic Acid
4 Citations (Scopus)
Fluids and Secretions
Aeromonas
Hemolysin Proteins
Cyclooxygenase 2
Prostaglandins E
70 Citations (Scopus)

MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II

Yamanaka, H., Kobayashi, H., Takahashi, E. & Okamoto, K., Dec 2008, In : Journal of Bacteriology. 190, 23, p. 7693-7698 6 p.

Research output: Contribution to journalArticle

Periplasm
Escherichia coli
Sexually Transmitted Diseases
Lepidium
Periplasmic Proteins
13 Citations (Scopus)

Studies on diarrheagenic Escherichia coli isolated from children with diarrhea in Myanmar

Takahashi, E., Sultan, Z., Shimada, S., Aung, W. W., Nyein, M. M., Oo, K. N., Nair, G. B., Takeda, Y. & Okamoto, K., Jan 2008, In : Microbiology and Immunology. 52, 1, p. 2-8 7 p.

Research output: Contribution to journalArticle

Myanmar
Diarrhea
Enteropathogenic Escherichia coli
Virulence
Escherichia coli
5 Citations (Scopus)

Toxin production by Aeromonas sobria in natural environments: River water vs. seawater

Khan, R., Takahashi, E., Nakura, H., Ansaruzzaman, M., Banik, S., Ramamurthy, T. & Okamoto, K., Dec 2008, In : Acta Medica Okayama. 62, 6, 2.

Research output: Contribution to journalArticle

Aeromonas
Seawater
Rivers
Water
Peptide Hydrolases
2007
8 Citations (Scopus)
DNA Adducts
Enzymes
Glucuronosyltransferase
Uridine Diphosphate
Cytochrome P-450 CYP1A1
11 Citations (Scopus)

Salt in surroundings influences the production of serine protease into milieu by Aeromonas sobria

Khan, R., Takahashi, E., Ramamurthy, T., Takeda, Y. & Okamoto, K., 2007, In : Microbiology and Immunology. 51, 10, p. 963-976 14 p.

Research output: Contribution to journalArticle

Aeromonas
Serine Proteases
Salts
Open Reading Frames
Proteins
10 Citations (Scopus)

Studies on the region involved in the transport activity of Escherichia coli TolC by chimeric protein analysis

Yamanaka, H., Tadokoro, S., Miyano, M., Takahashi, E., Kobayashi, H. & Okamoto, K., May 2007, In : Microbial Pathogenesis. 42, 5-6, p. 184-192 9 p.

Research output: Contribution to journalArticle

Escherichia coli
Proteins
Vibrio parahaemolyticus
Salmonella typhimurium
Gram-Negative Bacteria
2006
12 Citations (Scopus)

Cleavage specificity of the serine protease of Aeromonas sobria, a member of the kexin family of subtilases

Kobayashi, H., Takahashi, E., Oguma, K., Fujii, Y., Yamanaka, H., Negishi, T., Arimoto, S., Tsuji, T. & Okamoto, K., Mar 2006, In : FEMS Microbiology Letters. 256, 1, p. 165-170 6 p.

Research output: Contribution to journalArticle

Aeromonas
Serine Proteases
Furin
Peptide Hydrolases
Catalytic Domain
14 Citations (Scopus)

Inhibitory effects of beer on mutation in the ames test and DNA adduct formation in mouse organs induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP)

Arimoto, S., Ishida, R., Nakai, Y., Idei, C., Takata, J., Takahashi, E., Okamoto, K., Negishi, T. & Konuma, T., Jan 2006, In : Biological and Pharmaceutical Bulletin. 29, 1, p. 67-70 4 p.

Research output: Contribution to journalArticle

DNA Adducts
Mutation
Amines
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
Diet
4 Citations (Scopus)

Involvement of the drug efflux protein TolC in mutagenicity induced by MNNG or Trp-P-2

Takahashi, E., Okamoto, K., Arimoto, S., Yamanaka, H. & Negishi, T., Jun 16 2006, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 605, 1-2, p. 42-50 9 p.

Research output: Contribution to journalArticle

Methylnitronitrosoguanidine
Mutagens
Mutation
Pharmaceutical Preparations
Escherichia coli
2005
8 Citations (Scopus)

A hemolysin of Vibrio mimicus (VMH) stimulates cells to produce ATP and cyclic AMP which appear to be secretory mediators

Li, Y., Okamoto, K., Takahashi, E., Miyoshi, S., Shinoda, S., Tsuji, T. & Fujii, Y., 2005, In : Microbiology and Immunology. 49, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

Cyclic AMP
Adenosine Triphosphate
Chloride Channels
Glyburide
Erythrocyte Membrane
16 Citations (Scopus)

Novel antimutagenic factors derived from the edible mushroom Agrocybe cylindracea

Taira, K., Miyashita, Y., Okamoto, K., Arimoto, S., Takahashi, E. & Negishi, T., Oct 3 2005, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 586, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle

Agrocybe
Agaricales
Powders
Aflatoxin B1
Shiitake Mushrooms
2004
9 Citations (Scopus)

Amino-acid residues involved in the expression of the activity of Escherichia coli TolC

Yamanaka, H., Morisada, N., Miyano, M., Tsuge, H., Shinoda, S., Takahashi, E. & Okamoto, K., 2004, In : Microbiology and Immunology. 48, 10, p. 713-722 10 p.

Research output: Contribution to journalArticle

Escherichia coli
Hydrophobic and Hydrophilic Interactions
Amino Acids
Periplasm
Leucine
2002
50 Citations (Scopus)

Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin

Takahashi, E., Fujita, K. I., Kamataki, T., Arimoto, S., Okamoto, K. & Negishi, T., Oct 31 2002, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 508, 1-2, p. 147-156 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 Enzyme System
Carmine
Cytochrome P-450 CYP3A
Anthraquinones
Mutagens
2001
44 Citations (Scopus)

Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila

Takahashi, E., Marczylo, T. H., Watanabe, T., Nagai, S., Hayatsu, H. & Negishi, T., Sep 1 2001, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 480-481, p. 139-145 7 p.

Research output: Contribution to journalArticle

Anthraquinones
2-Acetylaminofluorene
Carcinogens
9,10-Dimethyl-1,2-benzanthracene
Food Additives