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Research Output 1998 2019

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2019
2 Citations (Scopus)

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

Kamiya, A., Hayama, Y., Kato, S., Shimomura, A., Shimomura, T., Irie, K., Kaneko, R., Yanagawa, Y., Kobayashi, K. & Ochiya, T., Jan 1 2019, In : Nature Neuroscience.

Research output: Contribution to journalArticle

Autonomic Pathways
Nerve Fibers
Breast Neoplasms
Neoplasms
Growth

Surface Modification with Lactadherin Augments the Attachment of Sonazoid Microbubbles to Glycoprotein IIb/IIIa

Otani, K., Kamiya, A., Miyazaki, T., Koga, A., Inatomi, A. & Harada-Shiba, M., Jan 1 2019, In : Ultrasound in Medicine and Biology.

Research output: Contribution to journalArticle

Microbubbles
Platelet Glycoprotein GPIIb-IIIa Complex
platelets
attachment
erythrocytes
2018
1 Citation (Scopus)

Simplified Preparation of αvβ3 Integrin-Targeted Microbubbles Based on a Clinically Available Ultrasound Contrast Agent: Validation in a Tumor-Bearing Mouse Model

Otani, K., Nishimura, H., Kamiya, A. & Harada-Shiba, M., May 1 2018, In : Ultrasound in Medicine and Biology. 44, 5, p. 1063-1073 11 p.

Research output: Contribution to journalArticle

Microbubbles
Integrins
Contrast Media
mice
tumors

Tonic aortic depressor nerve stimulation does not impede baroreflex dynamic characteristics concomitantly mediated by the stimulated nerve

Kawada, T., Turner, M. J., Shimizu, S., Kamiya, A., Shishido, T. & Sugimachi, M., Mar 1 2018, In : American journal of physiology. Regulatory, integrative and comparative physiology. 314, 3, p. R459-R467

Research output: Contribution to journalArticle

Baroreflex
Pressoreceptors
Pressure
Electric Stimulation
Arterial Pressure
2017
1 Citation (Scopus)
Carotid Sinus
Baroreflex
Inbred SHR Rats
Arterial Pressure
Electric Stimulation
1 Citation (Scopus)

Desipramine increases cardiac parasympathetic activity via α2-adrenergic mechanism in rats

Kawada, T., Akiyama, T., Shimizu, S., Fukumitsu, M., Kamiya, A. & Sugimachi, M., Jul 1 2017, In : Autonomic Neuroscience: Basic and Clinical. 205, p. 21-25 5 p.

Research output: Contribution to journalArticle

Desipramine
Adrenergic Agents
Acetylcholine
Norepinephrine Plasma Membrane Transport Proteins
Yohimbine
2 Citations (Scopus)

Effects of different input pressure waveforms on the carotid sinus baroreflexmediated sympathetic arterial pressure response in rats

Kawada, T., Shimizu, S., Yamamoto, H., Miyamoto, T., Kamiya, A., Shishido, T. & Sugimachi, M., Oct 1 2017, In : Journal of Applied Physiology. 123, 4, p. 914-921 8 p.

Research output: Contribution to journalArticle

Carotid Sinus
Arterial Pressure
Baroreflex
Pressure
Heart-Assist Devices
2 Citations (Scopus)

Sodium ion transport participates in non-neuronal acetylcholine release in the renal cortex of anesthetized rabbits

Shimizu, S., Akiyama, T., Kawada, T., Sata, Y., Turner, M. J., Fukumitsu, M., Yamamoto, H., Kamiya, A., Shishido, T. & Sugimachi, M., Sep 1 2017, In : Journal of Physiological Sciences. 67, 5, p. 587-593 7 p.

Research output: Contribution to journalArticle

Ion Transport
Acetylcholine
Sodium
Rabbits
Kidney
2016
7 Citations (Scopus)

Hybrid stage I palliation for hypoplastic left heart syndrome has no advantage on ventricular energetics: a theoretical analysis

Shimizu, S., Kawada, T., Une, D., Shishido, T., Kamiya, A., Sano, S. & Sugimachi, M., Jan 1 2016, In : Heart and Vessels. 31, 1, p. 105-113 9 p.

Research output: Contribution to journalArticle

Hypoplastic Left Heart Syndrome
Norwood Procedures
Pulmonary Artery
Heart Ventricles
Blood Vessels
6 Citations (Scopus)

Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis

Shimizu, S., Kawada, T., Une, D., Fukumitsu, M., Turner, M. J., Kamiya, A., Shishido, T. & Sugimachi, M., May 1 2016, In : Journal of Physiological Sciences. 66, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

Inferior Vena Cava
Pulmonary Artery
Hemodynamics
Pressure
Superior Vena Cava
2015
7 Citations (Scopus)

Acute effects of intravenous nifedipine or azelnidipine on open-loop baroreflex static characteristics in rats

Yamamoto, H., Kawada, T., Shimizu, S., Kamiya, A., Turner, M. J., Miyazaki, S. & Sugimachi, M., Apr 1 2015, In : Life Sciences. 126, p. 37-41 5 p.

Research output: Contribution to journalArticle

Baroreflex
Nifedipine
Rats
Carotid Sinus
Arterial Pressure
3 Citations (Scopus)

Guanfacine enhances cardiac acetylcholine release with little effect on norepinephrine release in anesthetized rabbits

Shimizu, S., Kawada, T., Akiyama, T., Turner, M. J., Shishido, T., Kamiya, A., Shirai, M. & Sugimachi, M., Jan 1 2015, In : Autonomic Neuroscience: Basic and Clinical. 187, p. 84-87 4 p.

Research output: Contribution to journalArticle

Guanfacine
Acetylcholine
Norepinephrine
Rabbits
Autonomic Pathways
18 Citations (Scopus)

Predominant role of neural arc in sympathetic baroreflex resetting of spontaneously hypertensive rats: Analysis of an open-loop baroreflex equilibrium diagram

Sata, Y., Kawada, T., Shimizu, S., Kamiya, A., Akiyama, T. & Sugimachi, M., Jan 1 2015, In : Circulation Journal. 79, 3, p. 592-599 8 p.

Research output: Contribution to journalArticle

Baroreflex
Inbred SHR Rats
Carotid Sinus
Arterial Pressure
Pressure
2014

High-cut characteristics of the baroreflex neural arc in rats

Kawada, T., Shimizu, S., Li, M., Zheng, C., Uemura, K., Kamiya, A. & Sugimachi, M., Jan 1 2014, In : Transactions of Japanese Society for Medical and Biological Engineering. 52, p. O-406-O-407

Research output: Contribution to journalArticle

Rats
Derivatives
White noise
Transfer functions
4 Citations (Scopus)

Medetomidine suppresses cardiac and gastric sympathetic nerve activities but selectively activates cardiac vagus nerve

Shimizu, S., Akiyama, T., Kawada, T., Kamiya, A., Turner, M. J., Yamamoto, H., Shishido, T., Shirai, M. & Sugimachi, M., Jan 1 2014, In : Circulation Journal. 78, 6, p. 1405-1413 9 p.

Research output: Contribution to journalArticle

Medetomidine
Vagus Nerve
Stomach
Acetylcholine
Norepinephrine
6 Citations (Scopus)

Systems physiology of the baroreflex during orthostatic stress: From animals to humans

Kamiya, A., Kawada, T. & Sugimachi, M., Jan 1 2014, In : Frontiers in Physiology. 5 JUL, 00256.

Research output: Contribution to journalArticle

Baroreflex
Arterial Pressure
Dizziness
Pressoreceptors
Pressure
2013
11 Citations (Scopus)

Effects of cilnidipine on sympathetic outflow and sympathetic arterial pressure and heart rate regulations in rats

Yamamoto, H., Kawada, T., Shimizu, S., Kamiya, A., Miyazaki, S. & Sugimachi, M., Jul 10 2013, In : Life Sciences. 92, 24-26, p. 1202-1207 6 p.

Research output: Contribution to journalArticle

Rats
Arterial Pressure
Heart Rate
Carotid Sinus
Pressoreceptors
3 Citations (Scopus)

High-frequency dominant depression of peripheral vagal control of heart rate in rats with chronic heart failure

Kawada, T., Li, M., Shimizu, S., Kamiya, A., Uemura, K., Turner, M. J., Mizuno, M. & Sugimachi, M., Mar 1 2013, In : Acta Physiologica. 207, 3, p. 494-502 9 p.

Research output: Contribution to journalArticle

Vagus Nerve Stimulation
Heart Failure
Heart Rate
Control Groups
Linear Models
8 Citations (Scopus)

Sympathetic afferent stimulation inhibits central vagal activation induced by intravenous medetomidine in rats

Kawada, T., Akiyama, T., Shimizu, S., Kamiya, A., Uemura, K., Turner, M. J., Shirai, M. & Sugimachi, M., Jan 1 2013, In : Acta Physiologica. 209, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

Medetomidine
Acetylcholine
Adrenergic Agonists
Adrenergic Agents
Stellate Ganglion
2012
8 Citations (Scopus)

Adaptation of the respiratory controller contributes to the attenuation of exercise hyperpnea in endurance-trained athletes

Miyamoto, T., Inagaki, M., Takaki, H., Kawada, T., Shishido, T., Kamiya, A. & Sugimachi, M., Jan 1 2012, In : European Journal of Applied Physiology. 112, 1, p. 237-251 15 p.

Research output: Contribution to journalArticle

Athletes
Exercise
Ventilation
Carbon Monoxide
Hyperoxia
12 Citations (Scopus)

Central vagal activation by alpha2-adrenergic stimulation is impaired in spontaneously hypertensive rats

Kawada, T., Akiyama, T., Shimizu, S., Kamiya, A., Uemura, K., Sata, Y., Shirai, M. & Sugimachi, M., Sep 1 2012, In : Acta Physiologica. 206, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

Inbred SHR Rats
Adrenergic Agents
Medetomidine
Acetylcholine
Inbred WKY Rats
18 Citations (Scopus)

Medetomidine, an α2-adrenergic agonist, activates cardiac vagal nerve through modulation of baroreflex control

Shimizu, S., Akiyama, T., Kawada, T., Sata, Y., Mizuno, M., Kamiya, A., Shishido, T., Inagaki, M., Shirai, M., Sano, S. & Sugimachi, M., Jan 2012, In : Circulation Journal. 76, 1, p. 152-159 8 p.

Research output: Contribution to journalArticle

Medetomidine
Adrenergic Agonists
Baroreflex
Acetylcholine
Blood Pressure
2011
22 Citations (Scopus)

Centrally administered ghrelin activates cardiac vagal nerve in anesthetized rabbits

Shimizu, S., Akiyama, T., Kawada, T., Sonobe, T., Kamiya, A., Shishido, T., Tokudome, T., Hosoda, H., Shirai, M., Kangawa, K. & Sugimachi, M., Jul 5 2011, In : Autonomic Neuroscience: Basic and Clinical. 162, 1-2, p. 60-65 6 p.

Research output: Contribution to journalArticle

Ghrelin
Rabbits
Dialysis Solutions
Acetylcholine
Norepinephrine
19 Citations (Scopus)

Closed-loop spontaneous baroreflex transfer function is inappropriate for system identification of neural arc but partly accurate for peripheral arc: Predictability analysis

Kamiya, A., Kawada, T., Shimizu, S. & Sugimachi, M., Apr 1 2011, In : Journal of Physiology. 589, 7, p. 1769-1790 22 p.

Research output: Contribution to journalArticle

Baroreflex
Arterial Pressure
Pressure
Pressoreceptors
Chloralose
1 Citation (Scopus)
Carotid Sinus
Baroreflex
Rats
Feedback
Arterial Pressure
12 Citations (Scopus)

Contrasting effects of moderate vagal stimulation on heart rate and carotid sinus baroreflex-mediated sympathetic arterial pressure regulation in rats

Kawada, T., Shimizu, S., Li, M., Kamiya, A., Uemura, K., Sata, Y., Yamamoto, H. & Sugimachi, M., Sep 26 2011, In : Life Sciences. 89, 13-14, p. 498-503 6 p.

Research output: Contribution to journalArticle

Pressure regulation
Vagus Nerve Stimulation
Carotid Sinus
Baroreflex
Rats
20 Citations (Scopus)

Dynamic characteristics of baroreflex neural and peripheral arcs are preserved in spontaneously hypertensive rats

Kawada, T., Shimizu, S., Kamiya, A., Sata, Y., Uemura, K. & Sugimachi, M., Jan 1 2011, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300, 1

Research output: Contribution to journalArticle

Baroreflex
Inbred SHR Rats
Arterial Pressure
Carotid Sinus
Pressure
8 Citations (Scopus)

Exercise training augments the dynamic heart rate response to vagal but not sympathetic stimulation in rats

Mizuno, M., Kawada, T., Kamiya, A., Miyamoto, T., Shimizu, S., Shishido, T., Smith, S. A. & Sugimachi, M., Apr 1 2011, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300, 4

Research output: Contribution to journalArticle

Heart Rate
Exercise
Analysis of Variance
13 Citations (Scopus)

Involvement of the mechanoreceptors in the sensory mechanisms of manual and electrical acupuncture

Yamamoto, H., Kawada, T., Kamiya, A., Miyazaki, S. & Sugimachi, M., Feb 24 2011, In : Autonomic Neuroscience: Basic and Clinical. 160, 1-2, p. 27-31 5 p.

Research output: Contribution to journalArticle

Mechanoreceptors
Acupuncture
Electroacupuncture
Gadolinium
Nociceptors
8 Citations (Scopus)

Norwood procedure with non-valved right ventricle to pulmonary artery shunt improves ventricular energetics despite the presence of diastolic regurgitation: A theoretical analysis

Shimizu, S., Une, D., Shishido, T., Kamiya, A., Kawada, T., Sano, S. & Sugimachi, M., Nov 2011, In : Journal of Physiological Sciences. 61, 6, p. 457-465 9 p.

Research output: Contribution to journalArticle

Norwood Procedures
Pulmonary Artery
Heart Ventricles
Blalock-Taussig Procedure
Hypoplastic Left Heart Syndrome
2010
6 Citations (Scopus)

Both skeletonized and pedicled internal thoracic arteries supply adequate graft flow after coronary artery bypass grafting even during intense sympathoexcitation

Une, D., Shimizu, S., Kamiya, A., Kawada, T., Shishido, T. & Sugimachi, M., Nov 1 2010, In : Journal of Physiological Sciences. 60, 6, p. 407-413 7 p.

Research output: Contribution to journalArticle

Mammary Arteries
Coronary Artery Bypass
Transplants
Stellate Ganglion
Vasoconstriction
11 Citations (Scopus)

Dynamic characteristics of heart rate control by the autonomic nervous system in rats

Mizuno, M., Kawada, T., Kamiya, A., Miyamoto, T., Shimizu, S., Shishido, T., Smith, S. A. & Sugimachi, M., Sep 1 2010, In : Experimental Physiology. 95, 9, p. 919-925 7 p.

Research output: Contribution to journalArticle

Autonomic Nervous System
Heart Rate
Vagus Nerve Stimulation
Mammals
13 Citations (Scopus)

In vivo direct monitoring of interstitial norepinephrine levels at the sinoatrial node

Shimizu, S., Akiyama, T., Kawada, T., Shishido, T., Mizuno, M., Kamiya, A., Yamazaki, T., Sano, S. & Sugimachi, M., Jan 15 2010, In : Autonomic Neuroscience: Basic and Clinical. 152, 1-2, p. 115-118 4 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Norepinephrine
Dialysis Solutions
Desipramine
Microdialysis
3 Citations (Scopus)

Large conductance Ca2+-activated K+ channels inhibit vagal acetylcholine release at the rabbit sinoatrial node

Kawada, T., Akiyama, T., Shimizu, S., Kamiya, A., Uemura, K., Sata, Y., Shirai, M. & Sugimachi, M., Aug 1 2010, In : Autonomic Neuroscience: Basic and Clinical. 156, 1-2, p. 149-151 3 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Sinoatrial Node
Acetylcholine
Large-Conductance Calcium-Activated Potassium Channels
Rabbits
36 Citations (Scopus)

Open-loop dynamic and static characteristics of the carotid sinus baroreflex in rats with chronic heart failure after myocardial infarction

Kawada, T., Li, M., Kamiya, A., Shimizu, S., Uemura, K., Yamamoto, H. & Sugimachi, M., Jul 1 2010, In : Journal of Physiological Sciences. 60, 4, p. 283-298 16 p.

Research output: Contribution to journalArticle

Carotid Sinus
Baroreflex
Heart Failure
Myocardial Infarction
Arterial Pressure
5 Citations (Scopus)
Baroreflex
Rabbits
Posture
Kidney
Heart Rate
5 Citations (Scopus)

Right ventricular stiffness constant as a predictor of postoperative hemodynamics in patients with hypoplastic right ventricle: A theoretical analysis

Shimizu, S., Shishido, T., Une, D., Kamiya, A., Kawada, T., Sano, S. & Sugimachi, M., May 2010, In : Journal of Physiological Sciences. 60, 3, p. 205-212 8 p.

Research output: Contribution to journalArticle

Heart Ventricles
Hemodynamics
Fontan Procedure
Atrial Pressure
Ownership
2009
12 Citations (Scopus)

Angiotensin II disproportionally attenuates dynamic vagal and sympathetic heart rate controls

Kawada, T., Mizuno, M., Shimizu, S., Uemura, K., Kamiya, A. & Sugimachi, M., May 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 5

Research output: Contribution to journalArticle

Angiotensin II
Heart Rate
Heart Failure
Vagotomy
Denervation
23 Citations (Scopus)

Detection of endogenous acetylcholine release during brief ischemia in the rabbit ventricle: A possible trigger for ischemic preconditioning

Kawada, T., Akiyama, T., Shimizu, S., Kamiya, A., Uemura, K., Li, M., Shirai, M. & Sugimachi, M., Oct 7 2009, In : Life Sciences. 85, 15-16, p. 597-601 5 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
Acetylcholine
Ischemia
Rabbits
Coronary Occlusion
17 Citations (Scopus)

High levels of circulating angiotensin II shift the open-loop baroreflex control of splanchnic sympathetic nerve activity, heart rate and arterial pressure in anesthetized rats

Kawada, T., Kamiya, A., Li, M., Shimizu, S., Uemura, K., Yamamoto, H. & Sugimachi, M., Nov 1 2009, In : Journal of Physiological Sciences. 59, 6, p. 447-455 9 p.

Research output: Contribution to journalArticle

Splanchnic Nerves
Baroreflex
Angiotensin II
Arterial Pressure
Heart Rate
27 Citations (Scopus)

In vivo direct monitoring of vagal acetylcholine release to the sinoatrial node

Shimizu, S., Akiyama, T., Kawada, T., Shishido, T., Yamazaki, T., Kamiya, A., Mizuno, M., Sano, S. & Sugimachi, M., Jun 15 2009, In : Autonomic Neuroscience: Basic and Clinical. 148, 1-2, p. 44-49 6 p.

Research output: Contribution to journalArticle

Sinoatrial Node
Acetylcholine
Dialysis Solutions
Vagus Nerve Stimulation
Heart Atria
7 Citations (Scopus)

Servo-controlled hind-limb electrical stimulation for short-term arterial pressure control

Kawada, T., Shimizu, S., Yamamoto, H., Shishido, T., Kamiya, A., Miyamoto, T., Sunagawa, K. & Sugimachi, M., May 1 2009, In : Circulation Journal. 73, 5, p. 851-859 9 p.

Research output: Contribution to journalArticle

Electric Stimulation
Arterial Pressure
Extremities
Acupuncture
Cardiovascular System
14 Citations (Scopus)
Head
Muscles
Tibial Nerve
Epinephrine
Healthy Volunteers
2008
4 Citations (Scopus)

Accentuated antagonism in vagal heart rate control mediated through muscarinic potassium channels

Mizuno, M., Kamiya, A., Kawada, T., Miyamoto, T., Shimizu, S., Shishido, T. & Sugimachi, M., Dec 1 2008, In : Journal of Physiological Sciences. 58, 6, p. 381-388 8 p.

Research output: Contribution to journalArticle

Potassium Channels
Cholinergic Agents
Heart Rate
Vagotomy
Denervation
2 Citations (Scopus)

Contrasting effects of presynaptic α2-adrenergic autoinhibition and pharmacologic augmentation of presynaptic inhibition on sympathetic heart rate control

Miyamoto, T., Kawada, T., Yanagiya, Y., Akiyama, T., Kamiya, A., Mizuno, M., Takaki, H., Sunagawa, K. & Sugimachi, M., Nov 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 5

Research output: Contribution to journalArticle

Adrenergic Agents
Yohimbine
Heart Rate
Clonidine
Rabbits
3 Citations (Scopus)

Decoding rule from vasoconstrictor skin sympathetic nerve activity to nonglabrous skin blood flow in humans at normothermic rest

Kamiya, A., Michikami, D., Iwase, S. & Mano, T., Jul 4 2008, In : Neuroscience Letters. 439, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

Vasoconstrictor Agents
Skin
Laser-Doppler Flowmetry
Supine Position
14 Citations (Scopus)

Electroacupuncture changes the relationship between cardiac and renal sympathetic nerve activities in anesthetized cats

Yamamoto, H., Kawada, T., Kamiya, A., Kita, T. & Sugimachi, M., Dec 15 2008, In : Autonomic Neuroscience: Basic and Clinical. 144, 1-2, p. 43-49 7 p.

Research output: Contribution to journalArticle

Electroacupuncture
Cats
Kidney
Vagotomy
Denervation
5 Citations (Scopus)
Acupuncture
Baroreflex
Heart Failure
Carotid Sinus
Acupuncture Points
8 Citations (Scopus)

Muscle mechanoreflex augments arterial baroreflex-mediated dynamic sympathetic response to carotid sinus pressure

Yamamoto, K., Kawada, T., Kamiya, A., Takaki, H., Shishido, T., Sunagawa, K. & Sugimachi, M., Sep 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 3

Research output: Contribution to journalArticle

Carotid Sinus
Baroreflex
Pressure
Muscles
Arterial Pressure
5 Citations (Scopus)

Upright tilt resets dynamic transfer function of baroreflex neural arc to minify the pressure disturbance in total baroreflex control

Kamiya, A., Kawada, T., Yamamoto, K., Mizuno, M., Shimizu, S. & Sugimachi, M., Jun 1 2008, In : Journal of Physiological Sciences. 58, 3, p. 189-198 10 p.

Research output: Contribution to journalArticle

Baroreflex
Pressure
Arterial Pressure
Fluid Shifts
Posture