Akira Shimada

  • 1969 Citations
  • 22 h-Index
19972020

Research output per year

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Research Output

  • 1969 Citations
  • 22 h-Index
  • 104 Article
  • 22 Letter
  • 3 Comment/debate
  • 2 Review article

[Bone marrow findings of childhood aplastic anemia: analyses of 140 cases by central reviewers].

Hama, A., Yoshimi, A., Sakaguchi, H., Doisaki, S., Muramatsu, H., Shimada, A., Takahashi, Y., Nozawa, K., Ito, M., Tsuchida, M., Manabe, A., Ohara, A. & Kojima, S., Aug 2011, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 52, 8, p. 653-658 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Aberrant expression of double-stranded RNA-dependent protein kinase in hepatocytes of chronic hepatitis and differentiated hepatocellular carcinoma

Shimada, A., Shiota, G., Miyata, H., Kamahora, T., Kawasaki, H., Shiraki, K., Hino, S. & Terada, T., Oct 1 1998, In : Cancer Research. 58, 19, p. 4434-4438 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Aberrant phosphorylation of STAT5 by granulocyte-macrophage colony-stimulating factor in infant cytomegalovirus infection mimicking juvenile myelomonocytic leukemia

Nishio, N., Takahashi, Y., Tanaka, M., Xu, Y., Yoshida, N., Sakaguchi, H., Doisaki, S., Hama, A., Muramatsu, H., Shimada, A. & Kojima, S., Sep 1 2011, In : Leukemia Research. 35, 9, p. 1261-1264 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

ABL kinase mutation and relapse in 4 pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia cases

Aoe, M., Shimada, A., Muraoka, M., Washio, K., Nakamura, Y., Takahashi, T., Imada, M., Watanabe, T., Okada, K., Nishiuchi, R., Miyamura, T., Chayama, K., Shibakura, M., Oda, M. & Morishima, T., May 2014, In : International journal of hematology. 99, 5, p. 609-615 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
5 Citations (Scopus)

Adults with germline CBL mutation complicated with juvenile myelomonocytic leukemia at infancy

Muraoka, M., Okuma, C., Kanamitsu, K., Ishida, H., Kanazawa, Y., Washio, K., Seki, M., Kato, M., Takita, J., Sato, Y., Ogawa, S., Tsukahara, H., Oda, M. & Shimada, A., Jun 1 2016, In : Journal of Human Genetics. 61, 6, p. 523-526 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Advanced-stage gastrointestinal stromal tumor treated with imatinib in a 12-year-old girl with a unique mutation of PDGFRA

Kuroiwa, M., Hiwatari, M., Hirato, J., Suzuki, N., Tsuchida, Y., Shimada, A., Shitara, T., Taki, T. & Hayashi, Y., Nov 2005, In : Journal of Pediatric Surgery. 40, 11, p. 1798-1801 4 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Adverse prognostic impact of KIT mutations in childhood CBF-AML: The results of the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05 trial

Tokumasu, M., Murata, C., Shimada, A., Ohki, K., Hayashi, Y., Saito, A. M., Fujimoto, J., Horibe, K., Nagao, M., Itoh, H., Kamikubo, Y., Nakayama, H., Kinoshita, A., Tomizawa, D., Taga, T., Tawa, A., Tanaka, S., Heike, T. & Adachi, S., Dec 1 2015, In : Leukemia. 29, 12, p. 2438-2441 4 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)

Age-associated difference in gene expression of paediatric acute myelomonocytic lineage leukaemia (FAB M4 and M5 subtypes) and its correlation with prognosis

Jo, A., Tsukimoto, I., Ishii, E., Asou, N., Mitani, S., Shimada, A., Igarashi, T., Hayashi, Y. & Ichikawa, H., Mar 1 2009, In : British Journal of Haematology. 144, 6, p. 917-929 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A Long-term survivor after congenital acute myeloid leukemia with t(8 ; 16)(p11 ; p13)

Hanada, T., Kanamitsu, K., Chayama, K., Miyamura, T., Kanazawa, Y., Muraoka, M., Washio, K., Imada, M., Kageyama, M., Takeuchi, A., Tamai, K., Oda, M. & Shimada, A., 2016, In : Acta medica Okayama. 70, 1, p. 31-35 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

AML1 mutation and FLT3-internal tandem duplication in leukemia transformed from myelodysplastic syndrome [1]

Shimada, A., Taketani, T., Kikuchi, A., Hanada, R., Arakawa, H., Kimura, H., Chen, Y. & Hayashi, Y., Sep 2007, In : Journal of Pediatric Hematology/Oncology. 29, 9, p. 666-667 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Appropriate dose reduction in induction therapy is essential for the treatment of infants with acute myeloid leukemia: A report from the japanese pediatric leukemia/lymphoma study group

Tomizawa, D., Tawa, A., Watanabe, T., Saito, A. M., Kudo, K., Taga, T., Iwamoto, S., Shimada, A., Terui, K., Moritake, H., Kinoshita, A., Takahashi, H., Nakayama, H., Kiyokawa, N., Isoyama, K., Mizutani, S., Hara, J., Horibe, K., Nakahata, T. & Adachi, S., Nov 2013, In : International journal of hematology. 98, 5, p. 578-588 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Autoimmune-like hepatitis following unrelated BMT successfully treated with rituximab

Narita, A., Muramatsu, H., Takahashi, Y., Sakaguchi, H., Doisaki, S., Nishio, N., Hama, A., Shimada, A., Ito, M. & Kojima, S., Apr 2012, In : Bone Marrow Transplantation. 47, 4, p. 600-602 3 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)

CD20-negative Epstein-Barr virus-associated post-transplant lymphoproliferative disease refractory to rituximab in a patient with severe aplastic anemia

Muramatsu, H., Takahashi, Y., Shimoyama, Y., Doisaki, S., Nishio, N., Ito, Y., Hama, A., Shimada, A., Yagasaki, H., Ito, M. & Kojima, S., Jun 1 2011, In : International journal of hematology. 93, 6, p. 779-781 3 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Childhood acute myeloid leukemia with bone marrow eosinophilia caused by t(16;21)(q24;q22)

Kawashima, N., Shimada, A., Taketani, T., Hayashi, Y., Yoshida, N., Matsumoto, K., Takahashi, Y., Kojima, S. & Kato, K., May 1 2012, In : International journal of hematology. 95, 5, p. 577-580 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Childhood cancer survivors: Anxieties felt after treatment and the need for continued support

Iwai, N., Shimada, A., Iwai, A., Yamaguchi, S., Tsukahara, H. & Oda, M., Nov 2017, In : Pediatrics International. 59, 11, p. 1140-1150 11 p.

Research output: Contribution to journalArticle

Clinical and biological features of paediatric acute myeloid leukaemia (AML) with primary induction failure in the Japanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study

Miyamura, T., Moritake, H., Nakayama, H., Tanaka, S., Tomizawa, D., Shiba, N., Saito, A. M., Tawa, A., Shimada, A., Iwamoto, S., Hayashi, Y., Koike, T., Horibe, K., Manabe, A., Mizutani, S., Taga, T. & Adachi, S., Apr 2019, In : British Journal of Haematology. 185, 2, p. 284-288 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Clinical characteristics and outcome of refractory/relapsed myeloid leukemia in children with Down syndrome

Taga, T., Saito, A. M., Kudo, K., Tomizawa, D., Terui, K., Moritake, H., Kinoshita, A., Iwamoto, S., Nakayama, H., Takahashi, H., Tawa, A., Shimada, A., Taki, T., Kigasawa, H., Koh, K. & Adachi, S., Aug 30 2012, In : Blood. 120, 9, p. 1810-1815 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Comparison of antitumor effects of multitargeted tyrosine kinase inhibitors in acute myelogenous leukemia

Hu, S., Niu, H., Minkin, P., Orwick, S., Shimada, A., Inaba, H., Dahl, G. V. H., Rubnitz, J. & Baker, S. D., 2008, In : Molecular cancer therapeutics. 7, 5, p. 1110-1120 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Congenital Glioblastoma with Distinct Clinical and Molecular Characteristics: Case Reports and a Literature Review

Kameda, M., Otani, Y., Ichikawa, T., Shimada, A., Ichimura, K. & Date, I., May 1 2017, In : World Neurosurgery. 101, p. 817.e5-817.e14

Research output: Contribution to journalArticle

7 Citations (Scopus)

Congenital pancreatoblastoma associated with β-catenin mutation

Ismael, O., Shimada, A., Hama, A., Takahashi, Y., Sato, Y., Hayakawa, M., Tsuchiya, H., Tainaka, T., Ono, Y., Kaneko, K., Ando, H., Sato, K. & Kojima, S., May 2012, In : Pediatric Blood and Cancer. 58, 5, p. 827 1 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes

Tomoyasu, C., Imamura, T., Tomii, T., Yano, M., Asai, D., Goto, H., Shimada, A., Sanada, M., Iwamoto, S., Takita, J., Minegishi, M., Inukai, T., Sugita, K. & Hosoi, H., Sep 1 2018, In : International journal of hematology. 108, 3, p. 312-318 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Correlation of cyp2c19 phenotype with voriconazole plasma concentration in children

Narita, A., Muramatsu, H., Sakaguchi, H., Doisaki, S., Tanaka, M., Hama, A., Shimada, A., Takahashi, Y., Yoshida, N., Matsumoto, K., Kato, K., Kudo, K., Furukawa-Hibi, Y., Yamada, K. & Kojima, S., Jul 1 2013, In : Journal of Pediatric Hematology/Oncology. 35, 5, p. e219-e223

Research output: Contribution to journalArticle

34 Citations (Scopus)

Cytomegalovirus retinitis during maintenance therapy for T-cell acute lymphoblastic leukemia

Wakai, K., Sano, H., Shimada, A., Shiozawa, Y., Park, M. J., Sotomatsu, M., Yanagisawa, R., Koike, K., Kozawa, K., Ryo, A., Tsukagoshi, H., Kimura, H. & Hayashi, Y., Mar 2013, In : Journal of Pediatric Hematology/Oncology. 35, 2, p. 162-163 2 p.

Research output: Contribution to journalLetter

12 Citations (Scopus)

De novo childhood myelodysplastic/myeloproliferative disease with unique molecular characteristics

Ismael, O., Shimada, A., Hama, A., Elshazley, M., Muramatsu, H., Goto, A., Sakaguchi, H., Tanaka, M., Takahashi, Y., Yinyan, X., Fukuda, M., Miyajima, Y., Yamashita, Y., Horibe, K., Hanada, R., Ito, M. & Kojima, S., Jul 2012, In : British Journal of Haematology. 158, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Desmoid-type fibromatosis in a boy with Down syndrome

Ishida, H., Chayama, K., Kanamitsu, K., Washio, K., Tanaka, T. & Shimada, A., May 2017, In : Pediatrics International. 59, 5, p. 624-626 3 p.

Research output: Contribution to journalArticle

Detection of APC mutations by a yeast-based protein truncation test (YPTT)

Suzuki, T., Ishioka, C., Kato, S., Mitachi, Y., Shimodaira, H., Sakayori, M., Shimada, A., Asamura, M. & Kanamaru, R., Apr 23 1998, In : Genes Chromosomes and Cancer. 21, 4, p. 290-297 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Detection of ATM gene mutation in human glioma cell line M059J by a rapid frameshift/stop codon assay in yeast

Tsuchida, R., Yamada, T., Takagi, M., Shimada, A., Ishioka, C., Katsuki, Y., Igarashi, T., Chessa, L., Delia, D., Teraoka, H. & Mizutani, S., Jan 1 2002, In : Radiation Research. 158, 2, p. 195-201 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Detection of heterozygous truncating mutations in the BRCA1 and APC genes by using a rapid screening assay in yeast

Ishioka, C., Suzuki, T., Fitzgerald, M., Krainer, M., Shimodaira, H., Shimada, A., Nomizu, T., Isselbacher, K. J., Haber, D. & Kanamaru, R., Mar 18 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 6, p. 2449-2453 5 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Detection of RBM15-MKL1 fusion was useful for diagnosis and monitoring of minimal residual disease in infant acute megakaryoblastic leukemia

Takeda, A., Shimada, A., Hamamoto, K., Yoshino, S., Nagai, T., Fujii, Y., Yamada, M., Nakamura, Y., Watanabe, T., Watanabe, Y., Yamamoto, Y., Sakakibara, K., Oda, M. & Morishima, T., 2014, In : Acta medica Okayama. 68, 2, p. 119-123 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer

Krainer, M., Silva-Arrieta, S., FitzGerald, M. G., Shimada, A., Ishioka, C., Kanamaru, R., MacDonald, D. J., Unsal, H., Finkelstein, D. M., Bowcock, A., Isselbacher, K. J. & Haber, D. A., May 28 1997, In : New England Journal of Medicine. 336, 20, p. 1416-1421 6 p.

Research output: Contribution to journalArticle

182 Citations (Scopus)

Discontinuation of l-asparaginase and poor response to prednisolone are associated with poor outcome of ETV6-RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia

Japan Association of Childhood Leukemia Study Group (JACLS), Apr 5 2019, In : International journal of hematology. 109, 4, p. 477-482 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia

Shiba, N., Taki, T., Park, M. J., Shimada, A., Sotomatsu, M., Adachi, S., Tawa, A., Horibe, K., Tsuchida, M., Hanada, R., Tsukimoto, I., Arakawa, H. & Hayashi, Y., Feb 2012, In : British Journal of Haematology. 156, 3, p. 413-414 2 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)

Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: Mutation classes correlate with progression to myeloid leukemia

Kanezaki, R., Toki, T., Terui, K., Xu, G., Wang, R. N., Shimada, A., Hama, A., Kanegane, H., Kawakami, K., Endo, M., Hasegawa, D., Kogawa, K., Adachi, S., Ikeda, Y., Iwamoto, S., Taga, T., Kosaka, Y., Kojima, S., Hayashi, Y. & Ito, E., Nov 25 2010, In : Blood. 116, 22, p. 4631-4638 8 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Effects of p51/p63 missense mutations on transcriptional activities of p53 downstream gene promoters

Kato, S., Shimada, A., Osada, M., Ikawa, S., Obinata, M., Nakagawara, A., Kanamaru, R. & Ishioka, C., Dec 1 1999, In : Cancer Research. 59, 23, p. 5908-5911 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Enhanced AKT phosphorylation of circulating B cells in patients with activated PI3Kδ syndrome

Asano, T., Okada, S., Tsumura, M., Yeh, T. W., Mitsui-Sekinaka, K., Tsujita, Y., Ichinose, Y., Shimada, A., Hashimoto, K., Wada, T., Imai, K., Ohara, O., Morio, T., Nonoyama, S. & Kobayashi, M., Apr 5 2018, In : Frontiers in immunology. 9, APR, 568.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Evaluation of the diagnostic accuracy of the stop codon (SC) assay for identifying protein-truncating mutations in the BRCA1 and BRCA2 genes in familial breast cancer

Sakayori, M., Kawahara, M., Shiraishi, K., Nomizu, T., Shimada, A., Kudo, T., Abe, R., Ohuchi, N., Takenoshita, S., Kanamaru, R. & Ishioka, C., 2003, In : Journal of Human Genetics. 48, 3, p. 130-137 8 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Everolimus for Treatment of Pseudomyogenic Hemangioendothelioma

Ozeki, M., Nozawa, A., Kanda, K., Hori, T., Nagano, A., Shimada, A., Miyazaki, T. & Fukao, T., 2017, In : Journal of Pediatric Hematology/Oncology. 39, 6, p. e328-e331

Research output: Contribution to journalArticle

15 Citations (Scopus)

EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia

Matsuo, H., Kajihara, M., Tomizawa, D., Watanabe, T., Saito, A. M., Fujimoto, J., Horibe, K., Kodama, K., Tokumasu, M., Itoh, H., Nakayama, H., Kinoshita, A., Taga, T., Tawa, A., Taki, T., Shiba, N., Ohki, K., Hayashi, Y., Yamashita, Y., Shimada, A. & 2 others, Tanaka, S. & Adachi, S., Nov 1 2014, In : Haematologica. 99, 11, p. e225-e227

Research output: Contribution to journalLetter

21 Citations (Scopus)

Excellent outcome of allogeneic bone marrow transplantation for Fanconi anemia using fludarabine-based reduced-intensity conditioning regimen

Shimada, A., Takahashi, Y., Muramatsu, H., Hama, A., Ismael, O., Narita, A., Sakaguchi, H., Doisaki, S., Nishio, N., Tanaka, M., Yoshida, N., Matsumoto, K., Kato, K., Watanabe, N. & Kojima, S., Jun 1 2012, In : International journal of hematology. 95, 6, p. 675-679 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Excellent outcomes of children with CML treated with imatinib mesylate compared to that in pre-imatinib era

Muramatsu, H., Takahashi, Y., Sakaguchi, H., Shimada, A., Nishio, N., Hama, A., Doisaki, S., Yagasaki, H., Matsumoto, K., Kato, K. & Kojima, S., Feb 2011, In : International journal of hematology. 93, 2, p. 186-191 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Excess treatment reduction including anthracyclines results in higher incidence of relapse in core binding factor acute myeloid leukemia in children

Tomizawa, D., Tawa, A., Watanabe, T., Saito, A. M., Kudo, K., Taga, T., Iwamoto, S., Shimada, A., Terui, K., Moritake, H., Kinoshita, A., Takahashi, H., Nakayama, H., Koh, K., Kigasawa, H., Kosaka, Y., Miyachi, H., Horibe, K., Nakahata, T. & Adachi, S., Dec 2013, In : Leukemia. 27, 12, p. 2413-2416 4 p.

Research output: Contribution to journalLetter

33 Citations (Scopus)

Exchange transfusion and cytarabine for transient abnormal myelopoiesis in hydrops fetalis

Okamura, T., Washio, Y., Yoshimoto, J., Tani, K., Tsukahara, H. & Shimada, A., 2019, In : Acta medica Okayama. 73, 2, p. 181-188 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma

Shimada, A., Hirato, J., Kuroiwa, M., Kikuchi, A., Hanada, R., Wakai, K. & Hayashi, Y., Feb 2008, In : Pediatric Blood and Cancer. 50, 2, p. 213-217 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome

Shimada, A., Xu, G., Toki, T., Kimura, H., Hayashi, Y. & Ito, E., Jan 1 2004, In : Blood. 103, 1, 1 p.

Research output: Contribution to journalLetter

41 Citations (Scopus)

FLT3-internal tandem duplication in a pediatric patient with t(8;21) acute myeloid leukemia

Kawamura, M., Kaku, H., Ito, T., Funata, N., Taki, T., Shimada, A. & Hayashi, Y., Dec 2010, In : Cancer Genetics and Cytogenetics. 203, 2, p. 292-296 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Fludarabine, cytarabine, granulocyte colony-stimulating factor and idarubicin for relapsed childhood acute myeloid leukemia

Nakayama, H., Tomizawa, D., Tanaka, S., Iwamoto, S., Shimada, A., Saito, A. M., Yamashita, Y., Moritake, H., Terui, K., Taga, T., Matsuo, H., Kosaka, Y., Koh, K., Hosoi, H., Kurosawa, H., Isoyama, K., Horibe, K., Mizutani, S. & Adachi, S., Oct 2017, In : Pediatrics International. 59, 10, p. 1046-1052 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Gene expression analysis of hypersensitivity to mosquito bite, chronic active EBV infection and NK/T-lymphoma/leukemia

Washio, K., Oka, T., Abdalkader, L., Muraoka, M., Shimada, A., Oda, M., Sato, H., Takata, K., Kagami, Y., Shimizu, N., Kato, S., Kimura, H., Nishizaki, K., Yoshino, T. & Tsukahara, H., Nov 2 2017, In : Leukemia and Lymphoma. 58, 11, p. 2683-2694 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia

Yoshida, N., Sakaguchi, H., Muramatsu, H., Okuno, Y., Song, C., Dovat, S., Shimada, A., Ozeki, M., Ohnishi, H., Teramoto, T., Fukao, T., Kondo, N., Takahashi, Y., Matsumoto, K., Kato, K. & Kojima, S., May 1 2017, In : Leukemia. 31, 5, p. 1221-1223 3 p.

Research output: Contribution to journalLetter

13 Citations (Scopus)