• 3157 Citations
  • 26 h-Index
1993 …2020

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2013

Serum oxidative-anti-oxidative stress balance is dysregulated in patients with hepatitis C virus-related hepatocellular carcinoma

Nishimura, M., Takaki, A., Tamaki, N., Maruyama, T., Onishi, H., Kobayashi, S., Nouso, K., Yasunaka, T., Koike, K., Hagihara, H., Kuwaki, K., Nakamura, S., Ikeda, F., Iwasaki, Y., Tomofuji, T., Morita, M. & Yamamoto, K., Oct 2013, In : Hepatology Research. 43, 10, p. 1078-1092 15 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis

Takeuchi, Y., Ikeda, F., Moritou, Y., Hagihara, H., Yasunaka, T., Kuwaki, K., Miyake, Y., Ohnishi, H., Nakamura, S., Shiraha, H., Takaki, A., Iwasaki, Y., Nouso, K. & Yamamoto, K., Mar 2013, In : Journal of Gastroenterology. 48, 3, p. 405-412 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Which patients respond best to hepatitis B vaccination after a hepatitis B virus-related liver transplantation?

Takaki, A., Yagi, T., Yasunaka, T., Sadamori, H., Shinoura, S., Umeda, Y., Yoshida, R., Sato, D., Nobuoka, D., Utsumi, M., Yasuda, Y., Nakayama, E., Miyake, Y., Ikeda, F., Shiraha, H., Nouso, K., Fujiwara, T. & Yamamoto, K., Dec 2013, In : Journal of Gastroenterology. 48, 12, p. 1373-1383 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

貧血を契機に発見され肝硬変に至っていた小児自己免疫性肝炎の1例

Takaki, A., 2013, In : 肝臓. 54, 10, p. 698-704 7 p.

Research output: Contribution to journalArticle

2012

A preliminary study for constructing a bioartificial liver device with induced pluripotent stem cell-derived hepatocytes

Iwamuro, M., Shiraha, H., Nakaji, S., Furutani, M., Kobayashi, N., Takaki, A. & Yamamoto, K., Dec 7 2012, In : BioMedical Engineering Online. 11, 93.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Clinical utility of serum fucosylated hemopexin in Japanese patients with hepatocellular carcinoma

Kobayashi, S., Nouso, K., Kinugasa, H., Takeuchi, Y., Tomoda, T., Miyahara, K., Hagihara, H., Kuwaki, K., Onishi, H., Nakamura, S., Ikeda, F., Miyake, Y., Shiraha, H., Takaki, A. & Yamamoto, K., Dec 2012, In : Hepatology Research. 42, 12, p. 1187-1195 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Des-γ-carboxyl prothrombin is associated with tumor angiogenesis in hepatocellular carcinoma

Matsubara, M., Shiraha, H., Kataoka, J., Iwamuro, M., Horiguchi, S., Nishina, S. I., Takaoka, N., Uemura, M., Takaki, A., Nakamura, S., Kobayashi, Y., Nouso, K. & Yamamoto, K., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, 10, p. 1602-1608 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Diagnostic role of 18F-fluorodeoxyglucose positron emission tomography for follicular lymphoma with gastrointestinal involvement

Iwamuro, M., Okada, H., Takata, K., Shinagawa, K., Fujiki, S., Shiode, J., Imagawa, A., Araki, M., Morito, T., Nishimura, M., Mizuno, M., Inaba, T., Suzuki, S., Kawai, Y., Yoshino, T., Kawahara, Y., Takaki, A. & Yamamoto, K., 2012, In : World journal of gastroenterology. 18, 44, p. 6427-6436 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Eradication of hepatitis c virus subgenomic replicon by interferon results in aberrant retinol-related protein expression

Koike, K., Takaki, A., Kato, N., Ouchida, M., Kanzaki, H., Yasunaka, T., Shiraha, H., Miyake, Y. & Yamamoto, K., 2012, In : Acta medica Okayama. 66, 6, p. 461-468 8 p.

Research output: Contribution to journalArticle

Fulminant hepatitis: Who survives without liver transplantation?

Miyake, Y., Yasunaka, T., Ikeda, F., Takaki, A., Nouso, K. & Yamamoto, K., Jan 2012, In : Hepatology Research. 42, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

Hepatitis B e antigen predicts delayed reduction of HBV DNA without viral breakthrough with adefovir dipivoxil and lamivudine: A 5-year study of patients with hepatitis B with lamivudine resistance

Ikeda, F., Baba, N., Takaguchi, K., Kubota, J., Miyoshi, K., Fujioka, S. I., Moritou, Y., Takeuchi, Y., Yasunaka, T., Miyake, Y., Takaki, A., Iwasaki, Y., Kobashi, H. & Yamamoto, K., Oct 2012, In : Journal of Medical Virology. 84, 10, p. 1562-1570 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice

Kawai, D., Takaki, A., Nakatsuka, A., Wada, J., Tamaki, N., Yasunaka, T., Koike, K., Tsuzaki, R., Matsumoto, K., Miyake, Y., Shiraha, H., Morita, M., Makino, H. & Yamamoto, K., Sep 2012, In : Hepatology. 56, 3, p. 912-921 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Peritoneovenous shunting for refractory ascites results in worsening of nephrotic syndrome

Takaki, A., Maeshima, Y., Yagi, T., Katayama, A., Hinamoto, N., Akagi, S., Sugiyama, H., Tomoda, T., Iwasaki, Y., Yasunaka, T., Ikeda, F., Miyake, Y., Kobashi, H., Hirano, A., Makino, H. & Yamamoto, K., Oct 2012, In : Hepatology Research. 42, 10, p. 1048-1053 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Risk factors for recurrence after transarterial chemoembolization for early-stage hepatocellular carcinoma

Kinugasa, H., Nouso, K., Takeuchi, Y., Yasunaka, T., Onishi, H., Nakamura, S. I., Shiraha, H., Kuwaki, K., Hagihara, H., Ikeda, F., Miyake, Y., Takaki, A. & Yamamoto, K., Apr 2012, In : Journal of Gastroenterology. 47, 4, p. 421-426 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma

Tanaka, S., Shiraha, H., Nakanishi, Y., Nishina, S. I., Matsubara, M., Horiguchi, S., Takaoka, N., Iwamuro, M., Kataoka, J., Kuwaki, K., Hagihara, H., Toshimori, J., Ohnishi, H., Takaki, A., Nakamura, S., Nouso, K., Yagi, T. & Yamamoto, K., Dec 1 2012, In : International Journal of Cancer. 131, 11, p. 2537-2546 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Serum levels of soluble adhesion molecules as prognostic factors for acute liver failure

Ohnishi, A., Miyake, Y., Matsushita, H., Matsumoto, K., Takaki, A., Yasunaka, T., Koike, K., Ikeda, F., Shiraha, H., Nouso, K. & Yamamoto, K., Aug 2012, In : Digestion. 86, 2, p. 122-128 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Sirs score reflects clinical features of non-acetaminophen-related acute liver failure with hepatic coma

Miyake, Y., Yasunaka, T., Ikeda, F., Takaki, A., Nouso, K. & Yamamoto, K., 2012, In : Internal Medicine. 51, 8, p. 823-828 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2011

+49A/G polymorphism of cytotoxic T-lymphocyte antigen 4 gene in type 1 autoimmune hepatitis and primary biliary cirrhosis: A meta-analysis

Miyake, Y., Ikeda, F., Takaki, A., Nouso, K. & Yamamoto, K., Feb 2011, In : Hepatology Research. 41, 2, p. 151-159 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Additive improvement induced by bezafibrate in patients with primary biliary cirrhosis showing refractory response to ursodeoxycholic acid

Takeuchi, Y., Ikeda, F., Fujioka, S. I., Takaki, T., Osawa, T., Yasunaka, T., Miyake, Y., Takaki, A., Iwasaki, Y., Kobashi, H., Yamamoto, K. & Itoshima, T., Sep 2011, In : Journal of Gastroenterology and Hepatology (Australia). 26, 9, p. 1395-1401 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

Tatsukawa, M., Takaki, A., Shiraha, H., Koike, K., Iwasaki, Y., Kobashi, H., Fujioka, S. I., Sakaguchi, K. & Yamamoto, K., Oct 21 2011, In : BMC cancer. 11, 458.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Hepatocellular carcinoma occurring in hepatobiliary fibropolycystic disease

Kinugasa, H., Nouso, K., Kobayashi, Y., Yasunaka, T., Onishi, H., Nakamura, S. I., Shiraha, H., Takayama, H., Toshimori, J., Kuwaki, K., Hagihara, H., Miyake, Y., Ikeda, F., Takaki, A., Kobashi, H. & Yamamoto, K., Mar 2011, In : Hepatology Research. 41, 3, p. 277-281 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Long-term outcome and hepatocellular carcinoma development in chronic hepatitis B or cirrhosis patients after nucleoside analog treatment with entecavir or lamivudine

Kobashi, H., Miyake, Y., Ikeda, F., Yasunaka, T., Nishino, K., Moriya, A., Kubota, J., Nakamura, S., Takaki, A., Nouso, K., Yamada, G. & Yamamoto, K., May 2011, In : Hepatology Research. 41, 5, p. 405-416 12 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis

Nakanishi, Y., Shiraha, H., Nishina, S. I., Tanaka, S., Matsubara, M., Horiguchi, S., Iwamuro, M., Takaoka, N., Uemura, M., Kuwaki, K., Hagihara, H., Toshimori, J., Ohnishi, H., Takaki, A., Nakamura, S., Kobayashi, Y., Nouso, K., Yagi, T. & Yamamoto, K., Jan 4 2011, In : BMC cancer. 11, 3.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Predicting the treatment effect of sorafenib using serum angiogenesis markers in patients with hepatocellular carcinoma

Miyahara, K., Nouso, K., Tomoda, T., Kobayashi, S., Hagihara, H., Kuwaki, K., Toshimori, J., Onishi, H., Ikeda, F., Miyake, Y., Nakamura, S., Shiraha, H., Takaki, A. & Yamamoto, K., Nov 2011, In : Journal of Gastroenterology and Hepatology (Australia). 26, 11, p. 1604-1611 8 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Prognostic importance of fucosylated alpha-fetoprotein in hepatocellular carcinoma patients with low alpha-fetoprotein

Nouso, K., Kobayashi, Y., Nakamura, S., Kobayashi, S., Takayama, H., Toshimori, J., Kuwaki, K., Hagihara, H., Onishi, H., Miyake, Y., Ikeda, F., Shiraha, H., Takaki, A., Iwasaki, Y., Kobashi, H. & Yamamoto, K., Jul 2011, In : Journal of Gastroenterology and Hepatology (Australia). 26, 7, p. 1195-1200 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Prognostic model for hepatocellular carcinoma with time-dependent factors

Kuwaki, K., Nouso, K., Kobayashi, Y., Nakamura, S., Ito, Y. M., Iwadou, S., Hagihara, H., Yasunaka, T., Toshimori, J., Miyatake, H., Miyoshi, K., Onishi, H., Miyake, Y., Shoji, B., Takaki, A., Shiraha, H., Iwasaki, Y., Kobashi, H. & Yamamoto, K., Feb 22 2011, In : Acta medica Okayama. 65, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

Serum hepatitis B virus DNA before liver transplantation correlates with HBV reinfection rate even under successful low-dose hepatitis B immunoglobulin prophylaxis

Yasunaka, T., Takaki, A., Yagi, T., Iwasaki, Y., Sadamori, H., Koike, K., Hirohata, S., Tatsukawa, M., Kawai, D., Shiraha, H., Miyake, Y., Ikeda, F., Kobashi, H., Matsuda, H., Shinoura, S., Yoshida, R., Satoh, D., Utsumi, M., Onishi, T. & Yamamoto, K., Dec 2011, In : Hepatology International. 5, 4, p. 918-926 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Serum levels of platelet-derived growth factor-BB and vascular endothelial growth factor as prognostic factors for patients with fulminant hepatic failure

Takayama, H., Miyake, Y., Nouso, K., Ikeda, F., Shiraha, H., Takaki, A., Kobashi, H. & Yamamoto, K., Jan 2011, In : Journal of Gastroenterology and Hepatology (Australia). 26, 1, p. 116-121 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Stage of hepatocellular carcinoma is associated with periodontitis

Tamaki, N., Takaki, A., Tomofuji, T., Endo, Y., Kasuyama, K., Ekuni, D., Yasunaka, T., Yamamoto, K. & Morita, M., Nov 2011, In : Journal of Clinical Periodontology. 38, 11, p. 1015-1020 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2010

Acute hepatitis due to hepatitis e virus genotype 1 as an imported infectious disease in Japan

Miyahara, K., Miyake, Y., Yasunaka, T., Ikeda, F., Takaki, A., Iwasaki, Y., Kobashi, H., Kang, J. H., Takahashi, K., Arai, M. & Yamamoto, K., 2010, In : Internal Medicine. 49, 23, p. 2613-2616 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Amino acid substitutions of hepatitis C virus core protein are not associated with intracellular antiviral response to interferon-α in vitro

Ikeda, F., Dansako, H., Nishimura, G., Mori, K., Kawai, Y., Ariumi, Y., Miyake, Y., Takaki, A., Nouso, K., Iwasaki, Y., Ikeda, M., Kato, N. & Yamamoto, K., Oct 2010, In : Liver International. 30, 9, p. 1324-1331 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Autoimmune hepatitis with acute presentation in Japan

Miyake, Y., Iwasaki, Y., Kobashi, H., Yasunaka, T., Ikeda, F., Takaki, A. & Yamamoto, K., Jan 2010, In : Digestive and Liver Disease. 42, 1, p. 51-54 4 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Clinical features of autoimmune hepatitis diagnosed based on simplified criteria of the International Autoimmune Hepatitis Group

Miyake, Y., Iwasaki, Y., Kobashi, H., Yasunaka, T., Ikeda, F., Takaki, A. & Yamamoto, K., Mar 2010, In : Digestive and Liver Disease. 42, 3, p. 210-215 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Evolution of prognostic factors in hepatocellular carcinoma in Japan

Nouso, K., Kobayashi, Y., Nakamura, S., Kobayashi, S., Toshimori, J., Kuwaki, K., Hagihara, H., Onishi, H., Miyake, Y., Ikeda, F., Shiraha, H., Takaki, A., Iwasaki, Y., Kobashi, H. & Yamamoto, K., Feb 2010, In : Alimentary Pharmacology and Therapeutics. 31, 3, p. 407-414 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Hepatic toxicity and prognosis in hepatitis C virus-infected patients with diffuse large B-cell lymphoma treated with rituximab-containing chemotherapy regimens: A Japanese multicenter analysis

Ennishi, D., Maeda, Y., Niitsu, N., Kojima, M., Izutsu, K., Takizawa, J., Kusumoto, S., Okamoto, M., Yokoyama, M., Takamatsu, Y., Sunami, K., Miyata, A., Murayama, K., Sakai, A., Matsumoto, M., Shinagawa, K., Takaki, A., Matsuo, K., Kinoshita, T. & Tanimoto, M., Dec 9 2010, In : Blood. 116, 24, p. 5119-5125 7 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Hepatitis C virus NS4 protein impairs the Th1 polarization of immature dendritic cells

Takaki, A., Tatsukawa, M., Iwasaki, Y., Koike, K., Noguchi, Y., Shiraha, H., Sakaguchi, K., Nakayama, E. & Yamamoto, K., Aug 2010, In : Journal of Viral Hepatitis. 17, 8, p. 555-562 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Laparoscopic findings of reddish markings predict hepatocellular carcinoma in patients with hepatitis B virus-related liver disease

Shoji, B., Ikeda, F., Fujioka, S. I., Kobashi, H., Yasunaka, T., Miyake, Y., Shiraha, H., Takaki, A., Nouso, K., Iwasaki, Y. & Yamamoto, K., Nov 2010, In : Journal of Gastroenterology. 45, 11, p. 1172-1182 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
75 Citations (Scopus)
2009

Clinical features of antinuclear antibodies-negative type 1 autoimmune hepatitis

Miyake, Y., Iwasaki, Y., Kobashi, H., Yasunaka, T., Ikeda, F., Takaki, A., Okamoto, R., Takaguchi, K., Ikeda, H., Makino, Y., Ando, M., Sakaguchi, K. & Yamamoto, K., 2009, In : Hepatology Research. 39, 3, p. 241-246 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Clinical features of type 1 autoimmune hepatitis in adolescence and early adulthood

Miyake, Y., Iwasaki, Y., Kobashi, H., Yasunaka, T., Ikeda, F., Takaki, A., Okamoto, R., Takaguchi, K., Ikeda, H., Makino, Y., Sakaguchi, K., Ando, M. & Yamamoto, K., 2009, In : Hepatology Research. 39, 8, p. 766-771 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Efficacy of ursodeoxycholic acid for Japanese patients with autoimmune hepatitis

Miyake, Y., Iwasaki, Y., Kobashi, H., Yasunaka, T., Ikeda, F., Takaki, A., Okamoto, R., Takaguchi, K., Ikeda, H., Makino, Y., Ando, M., Sakaguchi, K. & Yamamoto, K., Dec 2009, In : Hepatology International. 3, 4, p. 556-562 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Feasibility and findings of colonoscopy for living-donor liver transplant candidates

Ishikawa, S., Kato, J., Kuriyama, M., Takemoto, K., Uraoka, T., Takaki, A., Yagi, T. & Sakaguchi, K., Jan 2009, In : Journal of Clinical Gastroenterology. 43, 1, p. 69-74 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Twist expression promotes migration and invasion in hepatocellular carcinoma

Matsuo, N., Shiraha, H., Fujikawa, T., Takaoka, N., Ueda, N., Tanaka, S., Nishina, S., Nakanishi, Y., Uemura, M., Takaki, A., Nakamura, S., Kobayashi, Y., Nouso, K., Yagi, T. & Yamamoto, K., Jul 18 2009, In : BMC cancer. 9, 240.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naive chronic hepatitis B

Kobashi, H., Fujioka, S. I., Kawaguchi, M., Kumada, H., Yokosuka, O., Hayashi, N., Suzuki, K., Okanoue, T., Sata, M., Tsubouchi, H., Sato, C., Kiyosawa, K., Tanikawa, K., Seriu, T., Ishikawa, H., Takaki, A., Iwasaki, Y., Osawa, T., Takaki, T., Sakaguchi, K. & 4 others, Shiratori, Y., Yamamoto, K., Tenney, D. J. & Omata, M., 2009, In : Hepatology International. 3, 2, p. 403-410 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2008

A 27-year-old man who died of acute liver failure probably due to trichloroethylene abuse

Takaki, A., Suzuki, H., Iwasaki, Y., Takigawa, T., Ogino, K., Matsuda, H., Yagi, T., Hanazaki, M., Nakatsuka, H., Katayama, H., Matsumi, M., Shoji, B., Terada, R., Kobashi, H. & Sakaguchi, K., Mar 2008, In : Journal of Gastroenterology. 43, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A prospective and comparative cohort study on efficacy and drug resistance during long-term lamivudine treatment for various stages of chronic hepatitis B and cirrhosis

Nishida, T., Kobashi, H., Fujioka, S. I., Fujio, K., Takaguchi, K., Ikeda, H., Kawaguchi, M., Ando, M., Araki, Y., Higashi, T., Shoji, B., Takaki, A., Iwasaki, Y., Sakaguchi, K., Shiratori, Y. & Yamamoto, K., May 2008, In : Journal of Gastroenterology and Hepatology (Australia). 23, 5, p. 794-803 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Exon 2 deletion splice variant of γ-glutamyl carboxylase causes des-γ-carboxy prothrombin production in hepatocellular carcinoma cell lines

Ueda, N., Shiraha, H., Fujikawa, T., Takaoka, N., Nakanishi, Y., Suzuki, M., Matsuo, N., Tanaka, S., Nishina, S. I., Uemura, M., Takaki, A., Shiratori, Y. & Yamamoto, K., Oct 2008, In : Molecular Oncology. 2, 3, p. 241-249 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)