• 3271 Citations
  • 27 h-Index
1993 …2020

Research output per year

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Research Output

2020

Decreased serum antioxidant marker is predictive of early recurrence in the same segment after radical ablation for hepatocellular carcinoma

Muro, T., Nakamura, S., Takaki, A., Onishi, H., Wada, N., Yasunaka, T., Uchida, D., Oyama, A., Adachi, T., Shiraha, H. & Okada, H., 2020, In : Acta medica Okayama. 74, 4, p. 275-283 9 p.

Research output: Contribution to journalArticle

Differences in autoimmune hepatitis based on inflammation localization

Takahashi, A., Ohira, H., Abe, K., Zeniya, M., Abe, M., Arinaga-Hino, T., Torimura, T., Yoshizawa, K., Takaki, A., Kang, J. H., Suzuki, Y., Nakamoto, N., Inui, A., Tanaka, A. & Takikawa, H., 2020, (Accepted/In press) In : Medical Molecular Morphology.

Research output: Contribution to journalArticle

Human Telomerase Reverse Transcriptase Gene Promoter Mutation in Serum of Patients with Hepatocellular Carcinoma

Ako, S., Nouso, K., Kinugasa, H., Matsushita, H., Terasawa, H., Adachi, T., Wada, N., Takeuchi, Y., Mandai, M., Onishi, H., Ikeda, F., Shiraha, H., Takaki, A., Fujioka, S., Mimura, T. & Okada, H., Apr 1 2020, In : Oncology (Switzerland). 98, 5, p. 311-317 7 p.

Research output: Contribution to journalArticle

Increasing incidence of acute autoimmune hepatitis: a nationwide survey in Japan

Takahashi, A., Ohira, H., Abe, K., Zeniya, M., Abe, M., Arinaga-Hino, T., Torimura, T., Yoshizawa, K., Takaki, A., Kang, J. H., Suzuki, Y., Nakamoto, N., Inui, A., Tanaka, A. & Takikawa, H., Dec 1 2020, In : Scientific reports. 10, 1, 14250.

Research output: Contribution to journalArticle

Open Access

Oxidative stress management in chronic liver diseases and hepatocellular carcinoma

Uchida, D., Takaki, A., Oyama, A., Adachi, T., Wada, N., Onishi, H. & Okada, H., Jun 2020, In : Nutrients. 12, 6, 1576.

Research output: Contribution to journalArticle

Open Access

Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA

Hirai, M., Kunugasa, H., Nouso, K., Yamamoto, S., Terasawa, H., Onishi, Y., Oyama, A., Adachi, T., Wada, N., Sakata, M., Yasunaka, T., Onishi, H., Shiraha, H., Takaki, A. & Okada, H., 2020, (Accepted/In press) In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalArticle

Severe colitis caused by hepatic arterial infusion chemotherapy with cisplatin for hepatocellular carcinoma

Yamamoto, S., Onishi, H., Oyama, A., Takaki, A. & Okada, H., 2020, In : Internal Medicine. 59, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

Open Access

Transition in the etiology of liver cirrhosis in Japan: a nationwide survey

Japan Etiology of Liver Cirrhosis Study Group in the 54th Annual Meeting of JSH, Mar 1 2020, In : Journal of Gastroenterology. 55, 3, p. 353-362 10 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2019

Adefovir dipivoxil-induced fanconi's syndrome and osteomalacia following multiple bone fractures in a patient with chronic Hepatitis B

Makita, T., Kanzaki, H., Onishi, H., Ikeda, A., Takaki, A., Wada, N., Takeuchi, Y., Yasunaka, T., Ikeda, F., Shiraha, H., Tanaka, Y., Nishihara, S., Murakawa, K., Kitamura, Y., Okada, H. & Sendoa, T., 2019, In : Yakugaku Zasshi. 139, 4, p. 641-645 5 p.

Research output: Contribution to journalArticle

Open Access

Alcohol and hepatocellular carcinoma

Matsushita, H. & Takaki, A., Apr 1 2019, In : BMJ Open Gastroenterology. 6, 1, e000260.

Research output: Contribution to journalReview article

Open Access
7 Citations (Scopus)

Analysis of 307 cases with drug-induced liver injury between 2010 and 2018 in Japan

Aiso, M., Takikawa, H., Tsuji, K., Kagawa, T., Watanabe, M., Tanaka, A., Sato, K., Sakisaka, S., Hiasa, Y., Takei, Y., Ohira, H., Ayada, M., Hashimoto, E., Kaneko, S., Ueno, Y., Ohmoto, K., Takaki, A., Torimura, T., Matsuzaki, Y., Tajiri, K. & 7 others, Yoneda, M., Ito, T., Kato, N., Ikejima, K., Mochida, S., Yasuda, H. & Sakamoto, N., Jan 2019, In : Hepatology Research. 49, 1, p. 105-110 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A Phase I/Ib trial of Ad-REIC in liver cancer: Study protocol

Oyama, A., Shiraha, H., Uchida, D., Iwamuro, M., Kato, H., Takaki, A., Ikeda, F., Onishi, H., Yasunaka, T., Takeuchi, Y., Wada, N., Iwasaki, Y., Sakata, M., Okada, H. & Kumon, H., Jan 1 2019, In : Future Oncology. 15, 31, p. 3547-3554 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation

Takahara, M., Takaki, A., Hiraoka, S., Adachi, T., Shimomura, Y., Matsushita, H., Nguyen, T. T. T., Koike, K., Ikeda, A., Takashima, S., Yamasaki, Y., Inokuchi, T., Kinugasa, H., Sugihara, Y., Harada, K., Eikawa, S., Morita, H., Udono, H. & Okada, H., Dec 1 2019, In : Scientific reports. 9, 1, 11934.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Efficacy and safety of glecaprevir and pibrentasvir treatment for 8 or 12 weeks in patients with recurrent hepatitis C after liver transplantation: a Japanese multicenter experience

Ueda, Y., Kobayashi, T., Ikegami, T., Miuma, S., Mizuno, S., Akamatsu, N., Takaki, A., Ishigami, M., Takatsuki, M., Sugawara, Y., Maehara, Y., Uemoto, S. & Seno, H., Jul 12 2019, In : Journal of Gastroenterology. 54, 7, p. 660-666 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Monitoring serum proangiogenic cytokines from hepatocellular carcinoma patients treated with sorafenib

on behalf of the Okayama Liver Cancer Group, Jun 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, 6, p. 1081-1087 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Paradoxical roles of oxidative stress response in the digestive system before and after carcinogenesis

Takaki, A., Kawano, S., Uchida, D., Takahara, M., Hiraoka, S. & Okada, H., Feb 2019, In : Cancers. 11, 2, 213.

Research output: Contribution to journalReview article

Open Access
7 Citations (Scopus)

POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33

Hitomi, Y., Ueno, K., Kawai, Y., Nishida, N., Kojima, K., Kawashima, M., Aiba, Y., Nakamura, H., Kouno, H., Kouno, H., Ohta, H., Sugi, K., Nikami, T., Yamashita, T., Katsushima, S., Komeda, T., Ario, K., Naganuma, A., Shimada, M., Hirashima, N. & 66 others, Yoshizawa, K., Makita, F., Furuta, K., Kikuchi, M., Naeshiro, N., Takahashi, H., Mano, Y., Yamashita, H., Matsushita, K., Tsunematsu, S., Yabuuchi, I., Nishimura, H., Shimada, Y., Yamauchi, K., Komatsu, T., Sugimoto, R., Sakai, H., Mita, E., Koda, M., Nakamura, Y., Kamitsukasa, H., Sato, T., Nakamuta, M., Masaki, N., Takikawa, H., Tanaka, A., Ohira, H., Zeniya, M., Abe, M., Kaneko, S., Honda, M., Arai, K., Arinaga-Hino, T., Hashimoto, E., Taniai, M., Umemura, T., Joshita, S., Nakao, K., Ichikawa, T., Shibata, H., Takaki, A., Yamagiwa, S., Seike, M., Sakisaka, S., Takeyama, Y., Harada, M., Senju, M., Yokosuka, O., Kanda, T., Ueno, Y., Ebinuma, H., Himoto, T., Murata, K., Shimoda, S., Nagaoka, S., Abiru, S., Komori, A., Migita, K., Ito, M., Yatsuhashi, H., Maehara, Y., Uemoto, S., Kokudo, N., Nagasaki, M., Tokunaga, K. & Nakamura, M., Dec 1 2019, In : Scientific reports. 9, 1, 102.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Predictive factors for successful vaccination against hepatitis B surface antigen in patients who have undergone orthotopic liver transplantation

Ikeda, A., Takaki, A., Yasunaka, T., Oyama, A., Adachi, T., Wada, N., Onishi, H., Ikeda, F., Shiraha, H., Yoshida, K., Kuise, T., Nobuoka, D., Yoshida, R., Umeda, Y., Yagi, T., Fujiwara, T. & Okada, H., 2019, In : Acta medica Okayama. 73, 1, p. 41-50 10 p.

Research output: Contribution to journalArticle

The efficacy and safety of steroids for preventing postembolization syndrome after transcatheter arterial chemoembolization of hepatocellular carcinoma

Kuwaki, K., Nouso, K., Miyashita, M., Makino, Y., Hagihara, H., Moriya, A., Adachi, T., Wada, N., Yasunaka, Y., Yasunaka, T., Takeuchi, Y., Onishi, H., Nakamura, S., Ikeda, F., Shiraha, H., Takaki, A. & Okada, H., 2019, In : Acta medica Okayama. 73, 4, p. 333-339 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1 Citation (Scopus)
2018

A case of celecoxib-induced multiple ulcers of the small intestine observed on capsule endoscopy

Aoyama, Y., Takahashi, S., Inaba, T., Colvin, M., Ishikawa, S., Wato, M., Kono, Y., Kawano, S., Takaki, A. & Okada, H., Oct 2018, In : GASTROENTEROLOGICAL ENDOSCOPY. 60, 10, p. 2297-2302 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

An activity survey of hepatitis medical care coordinators in Okayama prefecture, Japan

Namba, S., Ikeda, F., Akiyama, F., Ishihara, M., Shimomura, Y., Yamasaki, N., Inuyama, N., Koyama, M., Kamegawa, K., Okubo, S., Hasegawa, Y., Iwai, K., Sanki, A., Miura, R., Yano, K., Fujii, Y., Ohyama, A., Adachi, T., Wada, N., Yasunaka, Y. & 6 others, Yasunaka, T., Onishi, H., Shiraha, H., Takaki, A., Yamanoi, H. & Okada, H., 2018, In : Acta Hepatologica Japonica. 59, 11, p. 625-632 8 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Beneficial and paradoxical roles of anti-oxidative nutritional support for non-alcoholic fatty liver disease

Uchida, D., Takaki, A., Adachi, T. & Okada, H., Aug 2018, In : Nutrients. 10, 8, 977.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey

The Japan Autoimmune Hepatitis Study Group (JAIHSG), Sep 1 2018, In : Journal of Gastroenterology. 53, 9, p. 1079-1088 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Correction to: Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection (Journal of Gastroenterology, (2018), 53, 4, (566-575), 10.1007/s00535-017-1396-0)

Kumada, H., Watanabe, T., Suzuki, F., Ikeda, K., Sato, K., Toyoda, H., Atsukawa, M., Ido, A., Takaki, A., Enomoto, N., Kato, K., Alves, K., Burroughs, M., Redman, R., Pugatch, D., Pilot-Matias, T. J., Krishnan, P., Oberoi, R. K., Xie, W. & Chayama, K., May 1 2018, In : Journal of Gastroenterology. 53, 5, 1 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)

Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection

Kumada, H., Watanabe, T., Suzuki, F., Ikeda, K., Sato, K., Toyoda, H., Atsukawa, M., Ido, A., Takaki, A., Enomoto, N., Kato, K., Alves, K., Burroughs, M., Redman, R., Pugatch, D., Pilot-Matias, T. J., Krishnan, P., Oberoi, R. K., Xie, W. & Chayama, K., Apr 1 2018, In : Journal of Gastroenterology. 53, 4, p. 566-575 10 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Health-related quality of life in patients with autoimmune hepatitis: A questionnaire survey

Takahashi, A., Moriya, K., Ohira, H., Arinaga-Hino, T., Zeniya, M., Torimura, T., Abe, M., Takaki, A., Kang, J. H., Inui, A., Fujisawa, T., Yoshizawa, K., Suzuki, Y., Nakamoto, N., Koike, K., Yoshiji, H., Goto, A., Tanaka, A., Younossi, Z. M. & Takikawa, H., Oct 2018, In : PloS one. 13, 10, e0204772.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Mixed HCV infection of genotype 1b and other genotypes influences non-response during daclatasvir + asunaprevir combination Therapy

Wada, N., Ikeda, F., Mori, C., Takaguchi, K., Fujioka, S. I., Kobashi, H., Morimoto, Y., Kariyama, K., Sakaguchi, K., Hashimoto, N., Moriya, A., Kawaguchi, M., Miyatake, H., Hagihara, H., Kubota, J., Takayama, H., Takeuchi, Y., Yasunaka, T., Takaki, A., Iwasaki, Y. & 1 others, Okada, H., 2018, In : Acta medica Okayama. 72, 4, p. 401-406 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Non-alcoholic fatty liver disease in patients with autoimmune hepatitis

Japan AIH Study Group (JAIHSG), Apr 1 2018, In : JGH Open. 2, 2, p. 54-58 5 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Risk analysis for invasive fungal infection after living donor liver transplantation: Which patient needs potent prophylaxis?

Utsumi, M., Umeda, Y., Yagi, T., Nagasaka, T., Shinoura, S., Yoshida, R., Nobuoka, D., Kuise, T., Fuji, T., Takagi, K., Takaki, A. & Fujiwara, T., Dec 1 2018, In : Digestive Surgery. 36, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

Symptoms and health-related quality of life in Japanese patients with primary biliary cholangitis

Yagi, M., Tanaka, A., Abe, M., Namisaki, T., Yoshiji, H., Takahashi, A., Ohira, H., Komori, A., Yamagiwa, S., Kikuchi, K., Yasunaka, T., Takaki, A., Ueno, Y., Honda, A., Matsuzaki, Y. & Takikawa, H., Dec 1 2018, In : Scientific reports. 8, 1, 12542.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Transcatheter arterial chemoembolization to reduce size of hepatocellular carcinoma before radiofrequency ablation

Ako, S., Nakamura, S., Nouso, K., Dohi, C., Wada, N., Morimoto, Y., Takeuchi, Y., Yasunaka, T., Kuwaki, K., Onishi, H., Ikeda, F., Shiraha, H., Takaki, A. & Okada, H., 2018, In : Acta medica Okayama. 72, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Acute presentation of autoimmune hepatitis: A multicentre study with detailed histological evaluation in a large cohort of patients

Nguyen Canh, H., Harada, K., Ouchi, H., Sato, Y., Tsuneyama, K., Kage, M., Nakano, M., Yoshizawa, K., Takahashi, A., Abe, M., Kang, J. H., Koike, K., Inui, A., Fujisawa, T., Takaki, A., Arinaga-Hino, T., Torimura, T., Suzuki, Y., Fujiwara, K., Zeniya, M. & 3 others, Ohira, H., Tanaka, A. & Takikawa, H., Nov 2017, In : Journal of Clinical Pathology. 70, 11, p. 961-969 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Application of radiofrequency ablation for the treatment of intermediate-stage hepatocellular carcinoma

Nouso, K., Kariyama, K., Nakamura, S., Oonishi, A., Wakuta, A., Oyama, A., Ako, S., Dohi, C., Wada, N., Morimoto, Y., Takeuchi, Y., Kuwaki, K., Onishi, H., Ikeda, F., Shiraha, H., Takaki, A. & Okada, H., Mar 1 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 3, p. 695-700 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A sofosbuvir-based direct-acting antiviral treatment regimen exhibits a strong protective effect against post-liver transplantation chronic hepatitis C recurrence

Oyama, A., Takaki, A., Yasunaka, T., Adachi, T., Ikeda, F., Wada, N., Takeuchi, Y., Onishi, H., Nakamura, S., Shiraha, H., Takagi, K., Kuise, T., Nobuoka, D., Yoshida, R., Umeda, Y., Yoshida, M., Arimori, C., Yagi, T. & Okada, H., 2017, In : Acta Hepatologica Japonica. 58, 11, p. 599-604 6 p.

Research output: Contribution to journalArticle

Autoimmune hepatitis in Japan: trends in a nationwide survey

Autoimmune Hepatitis Study Group-Subgroup of the Intractable Hepato-Biliary Disease Study Group in Japan, May 1 2017, In : Journal of Gastroenterology. 52, 5, p. 631-640 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Corrigendum] Loss of Runt‑related transcription factor 3 induces resistance to 5‑fluorouracil and cisplatin in hepatocellular carcinoma

Kataoka, J., Shiraha, H., Horiguchi, S., Sawahara, H., Uchida, D., Nagahara, T., Iwamuro, M., Morimoto, H., Takeuchi, Y., Kuwaki, K., Onishi, H., Nakamura, S., Takaki, A., Nouso, K., Yagi, T., Yamamoto, K. & Okada, H., Mar 1 2017, In : Oncology reports. 37, 3, 1 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Early chimerism after liver transplantation reflects the clinical course of recurrent hepatitis C

Utsumi, M., Takaki, A., Umeda, Y., Koike, K., Napier, S. C., Watanabe, N., Shinoura, S., Yoshida, R., Nobuoka, D., Yasunaka, T., Oto, T., Araki, M., Yamamoto, K., Fujiwara, T. & Yagi, T., 2017, In : Annals of Transplantation. 22, p. 156-165 10 p.

Research output: Contribution to journalArticle

Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices

Saito, H., Ohmori, M., Iwamuro, M., Tanaka, T., Wada, N., Yasunaka, T., Takaki, A. & Okada, H., 2017, In : Internal Medicine. 56, 19, p. 2583-2588 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Living donor liver transplantation for acute liver failure: Comparing guidelines on the prediction of liver transplantation

Yoshida, K., Umeda, Y., Takaki, A., Nagasaka, T., Yoshida, R., Nobuoka, D., Kuise, T., Takagi, K., Yasunaka, T., Okada, H., Yagi, T. & Fujiwara, T., 2017, In : Acta medica Okayama. 71, 5, p. 381-390 10 p.

Research output: Contribution to journalArticle

Oxidative stress controlling agents are effective for small intestinal injuries induced by non-steroidal anti-inflammatory drugs

Kono, Y., Kawano, S., Takaki, A., Shimomura, Y., Onji, M., Ishikawa, H., Takahashi, S., Horii, J., Kobayashi, S., Kawai, D., Yamamoto, K. & Okada, H., Jan 1 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 1, p. 136-145 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Oxidative stress in nonalcoholic steatohepatitis

Takaki, A., Uchida, D. & Yamamoto, K., Jan 1 2017, Reactive Oxygen Species in Biology and Human Health. CRC Press, p. 349-361 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Promising therapeutic efficacy of a novel reduced expression in immortalized cells/dickkopf-3 expressing adenoviral vector for hepatocellular carcinoma

Sawahara, H., Shiraha, H., Uchida, D., Kato, H., Kato, R., Oyama, A., Nagahara, T., Iwamuro, M., Horiguchi, S., Tsutsumi, K., Mandai, M., Mimura, T., Wada, N., Takeuchi, Y., Kuwaki, K., Onishi, H., Nakamura, S., Watanabe, M., Sakaguchi, M., Takaki, A. & 5 others, Nouso, K., Yagi, T., Nasu, Y., Kumon, H. & Okada, H., Oct 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 10, p. 1769-1777 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Redox Signaling in NASH

Takaki, A., Uchida, D. & Yamamoto, K., Mar 23 2017, Liver Pathophysiology: Therapies and Antioxidants. Elsevier, p. 169-180 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter