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2020

Deep Learning of Cancer Stem Cell Morphology Using Conditional Generative Adversarial Networks

Aida, S., Okugawa, J., Fujisaka, S., Kasai, T., Kameda, H. & Sugiyama, T., Jun 19 2020, In : Biomolecules. 10, 6

Research output: Contribution to journalArticle

Open Access

Rapid and specific detection of oxidized LDL/β2GPI complexes via facile lateral flow immunoassay

Tan, X. W., Takenaka, F., Takekawa, H. & Mastuura, E., Jun 2020, In : Heliyon. 6, 6, e04114.

Research output: Contribution to journalArticle

Open Access

Sera anti-p53 antibody provides new information which explains the link between diabetes and cancer

Sauriasari, R., Sekar, A. P., Aisyah, N., Syahdi, R. R. & Matsuura, E., 2020, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 13, p. 325-331 7 p.

Research output: Contribution to journalArticle

Open Access

Tithonia diversifolia-derived orizabin suppresses cell adhesion, differentiation, and oxidized LDL accumulation by Akt signaling suppression via PTEN promotion in THP-1 cells

Ide, M., Yoshida, I., Kumagai, M., Mishima, T., Takahashi, Y., Fujita, K., Igarashi, T. & Matsuura, E., Jul 1 2020, In : Journal of Food Biochemistry. 44, 7, e13268.

Research output: Contribution to journalArticle

2019

A culture substratum with net-like polyamide fibers promotes the differentiation of mouse and human pluripotent stem cells to insulin-producing cells

Kaitsuka, T., Kojima, R., Kawabe, M., Noguchi, H., Shiraki, N., Kume, S. & Tomizawa, K., Jun 19 2019, In : Biomedical materials (Bristol, England). 14, 4, 1 p.

Research output: Contribution to journalArticle

A leucine zipper-based peptide hybrid delivers functional Nanog protein inside the cell nucleus

Hakata, Y., Michiue, H., Ohtsuki, T., Miyazawa, M. & Kitamatsu, M., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Clinical significance of buccal branches of the facial nerve and their relationship with the emergence of Stensen's duct: An anatomical study on adult Taiwanese cadavers

Tsai, C. H., Ting, C. C., Wu, S. Y., Chiu, J. Y., Chen, H., Igawa, K., Lan, T. H., Chen, C. M., Takato, T., Hoshi, K. & Ko, E. C., Nov 2019, In : Journal of Cranio-Maxillofacial Surgery. 47, 11, p. 1809-1818 10 p.

Research output: Contribution to journalArticle

Mitochondrial localization of PABPN1 in oculopharyngeal muscular dystrophy

Doki, T., Yamashita, S., Wei, F. Y., Hara, K., Yamamoto, T., Zhang, Z., Zhang, X., Tawara, N., Hino, H., Uyama, E., Kurashige, T., Maruyama, H., Tomizawa, K. & Ando, Y., Nov 1 2019, In : Laboratory Investigation. 99, 11, p. 1728-1740 13 p.

Research output: Contribution to journalArticle

Novel single-chain variant of antibody against mesothelin established by phage library

Yakushiji, H., Kobayashi, K., Takenaka, F., Kishi, Y., Shinohara, M., Akehi, M., Sasaki, T., Ohno, E. & Matsuura, E., Sep 1 2019, In : Cancer Science. 110, 9, p. 2722-2733 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells

Abe, T., La, T. M., Miyagaki, Y., Oya, E., Wei, F. Y., Sumida, K., Fujise, K., Takeda, T., Tomizawa, K., Takei, K. & Yamada, H., Feb 2019, In : International journal of oncology. 54, 2, p. 550-558 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Use of DNA-generated gold nanoparticles to radiosensitize and eradicate radioresistant glioma stem cells

Kunoh, T., Shimura, T., Kasai, T., Matsumoto, S., Mahmud, H., Khayrani, A. C., Seno, M., Kunoh, H. & Takada, J., Feb 1 2019, In : Nanotechnology. 30, 5, 055101.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2018

Boron neutron capture therapy combined with early successive bevacizumab treatments for recurrent malignant gliomas – A pilot study

Shiba, H., Takeuchi, K., Hiramatsu, R., Furuse, M., Nonoguchi, N., Kawabata, S., Kuroiwa, T., Kondo, N., Sakurai, Y., Suzuki, M., Ono, K., Oue, S., Ishikawa, E., Michiue, H. & Miyatake, S. I., Jan 1 2018, In : neurologia medico-chirurgica. 58, 12, p. 487-494 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion

Otani, Y., Ichikawa, T., Kurozumi, K., Inoue, S., Ishida, J., Oka, T., Shimizu, T., Tomita, Y., Hattori, Y., Uneda, A., Matsumoto, Y., Michiue, H. & Date, I., Feb 8 2018, In : Oncogene. 37, 6, p. 777-786 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells

Ono, K., Eguchi, T., Sogawa, C., Calderwood, S. K., Futagawa, J., Kasai, T., Seno, M., Okamoto, K., Sasaki, A. & Kozaki, K. I., Sep 2018, In : Journal of Cellular Biochemistry. 119, 9, p. 7350-7362 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons

Latt, H. M., Matsushita, H., Morino, M., Koga, Y., Michiue, H., Nishiki, T., Tomizawa, K. & Matsui, H., May 21 2018, In : Neuroscience. 379, p. 383-389 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Physical modification of carbon nanotubes with a dendrimer bearing terminal mercaptoundecahydrododecaborates (Na2B12H11S)

Yamagami, M., Tajima, T., Ishimoto, K., Miyake, H., Michiue, H. & Takaguchi, Y., Dec 2018, In : Heteroatom Chemistry. 29, 5-6, e21467.

Research output: Contribution to journalArticle

Regulation of mitochondrial iron homeostasis by sideroflexin 2

Mon, E. E., Wei, F. Y., Ahmad, R. N. R., Yamamoto, T., Moroishi, T. & Tomizawa, K., Jan 1 2018, (Accepted/In press) In : Journal of Physiological Sciences.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Sirtuin 7 is involved in the consolidation of fear memory in mice

Islam, M. S., Wei, F. Y., Ohta, K., Shigematsu, N., Fukuda, T., Tomizawa, K., Yoshizawa, T. & Yamagata, K., Jan 1 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 261-266 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Suppression effect on IFN-γ of adipose tissue-derived mesenchymal stem cells isolated from β2-microglobulin-deficient mice

Masuda, J., Takayama, E., Ichinohe, T., Strober, W., Mizuno-Kamiya, M., Ikawa, T., Kitani, A., Kawaki, H., Fuss, I., Kawamoto, H., Seno, A., Vaidyanath, A., Umemura, N., Mizutani, A., Kasai, T., Honjo, Y., Satoh, A., Murakami, H., Katsura, Y., Kondoh, N. & 1 others, Seno, M., Nov 2018, In : Experimental and Therapeutic Medicine. 16, 5, p. 4277-4282 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice

Watanabe, H., Watanabe, K. S., Liu, K., Hiramatsu, S., Zeggar, S., Katsuyama, E., Tatebe, N., Akahoshi, A., Takenaka, F., Hanada, T., Akehi, M., Sasaki, T., Sada, K. E., Matsuura, E., Nishibori, M. & Wada, J., Sep 15 2017, In : Molecular Therapy - Methods and Clinical Development. 6, p. 31-39 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cdk5rap1-mediated 2-methylthio-N6-isopentenyladenosine modification is absent from nuclear-derived RNA species

Fakruddin, M., Wei, F. Y., Emura, S., Matsuda, S., Yasukawa, T., Kang, D. & Tomizawa, K., 2017, In : Nucleic acids research. 45, 20, p. 11954-11961 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Akaike, T., Ida, T., Wei, F. Y., Nishida, M., Kumagai, Y., Alam, M. M., Ihara, H., Sawa, T., Matsunaga, T., Kasamatsu, S., Nishimura, A., Morita, M., Tomizawa, K., Nishimura, A., Watanabe, S., Inaba, K., Shima, H., Tanuma, N., Jung, M., Fujii, S. & 6 others, Watanabe, Y., Ohmuraya, M., Nagy, P., Feelisch, M., Fukuto, J. M. & Motohashi, H., Dec 1 2017, In : Nature communications. 8, 1, 1177.

Research output: Contribution to journalArticle

105 Citations (Scopus)

In vitro analysis of radioprotective effect of monoterpenes

Kudo, K. I., Hanafusa, T. & Ono, T., May 4 2017, (Accepted/In press) In : Journal of Radioanalytical and Nuclear Chemistry. p. 1-6 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

PIK3R1Met326Ile germline mutation correlates with cysteine-rich protein 61 expression and poor prognosis in glioblastoma

Otani, Y., Ishida, J., Kurozumi, K., Oka, T., Shimizu, T., Tomita, Y., Hattori, Y., Uneda, A., Matsumoto, Y., Michiue, H., Tomida, S., Matsubara, T., Ichikawa, T. & Date, I., Dec 1 2017, In : Scientific reports. 7, 1, 7391.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion

Takahashi, N., Wei, F. Y., Watanabe, S., Hirayama, M., Ohuchi, Y., Fujimura, A., Kaitsuka, T., Ishii, I., Sawa, T., Nakayama, H., Akaike, T. & Tomizawa, K., 2017, In : Nucleic acids research. 45, 1, p. 435-445 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma

Li, X., Xu, P., Wang, C., Xu, N., Xu, A., Xu, Y., Sadahira, T., Araki, M., Wada, K., Matsuura, E., Watanabe, M., Zheng, J., Sun, P., Huang, P., Nasu, Y. & Liu, C., 2017, In : Oncotarget. 8, 13, p. 21177-21186 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Synthesis of L-cysteine derivatives containing stable sulfur isotopes and application of this synthesis to reactive sulfur metabolome

Ono, K., Jung, M., Zhang, T., Tsutsuki, H., Sezaki, H., Ihara, H., Wei, F. Y., Tomizawa, K., Akaike, T. & Sawa, T., May 1 2017, In : Free Radical Biology and Medicine. 106, p. 69-79 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The immunological impact of chemotherapy on the tumor microenvironment of oral squamous cell carcinoma

Takakura, H., Domae, S., Ono, T. & Sasaki, A., 2017, In : Acta medica Okayama. 71, 3, p. 219-226 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ

Li, J., Xiu, Z., Wang, R., Yu, C., Chi, Y., Qin, J., Fu, C., Matsuura, E. & Liu, Q., May 15 2017, In : Life Sciences. 177, p. 27-40 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization

Hayashi, K., Michiue, H., Yamada, H., Takata, K., Nakayama, H., Wei, F. Y., Fujimura, A., Tazawa, H., Asai, A., Ogo, N., Miyachi, H., Nishiki, T. I., Tomizawa, K., Takei, K. & Matsui, H., Mar 18 2016, In : Scientific reports. 6, 23372.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Oxytocin Protects against Stress-Induced Cell Death in Murine Pancreatic β-Cells

Watanabe, S., Wei, F. Y., Matsunaga, T., Matsunaga, N., Kaitsuka, T. & Tomizawa, K., May 4 2016, In : Scientific reports. 6, 25185.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2015

A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1

Locke, J. M., Wei, F. Y., Tomizawa, K., Weedon, M. N. & Harries, L. W., Mar 6 2015, In : Diabetologia. 58, 4, p. 745-748 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A finite difference method for elastic wave scattering by a planar crack with contacting faces

Kimoto, K. & Ichikawa, Y., Jan 1 2015, In : Wave Motion. 52, p. 120-137 18 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A new theoretical mineral dissolution rate equation for physicochemical factors

Choi, J., Ichikawa, Y., Kimoto, K. & Chae, B. G., 2015, In : Geochemical Journal. 49, 5, p. 549-557 9 p.

Research output: Contribution to journalArticle

A novel leucine zipper motif-based hybrid peptide delivers a functional peptide cargo inside cells

Hakata, Y., Tsuchiya, S., Michiue, H., Ohtsuki, T., Matsui, H., Miyazawa, M. & Kitamatsu, M., Jan 7 2015, In : Chemical Communications. 51, 2, p. 413-416 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans

Wei, F. Y., Zhou, B., Suzuki, T., Miyata, K., Ujihara, Y., Horiguchi, H., Takahashi, N., Xie, P., Michiue, H., Fujimura, A., Kaitsuka, T., Matsui, H., Koga, Y., Mohri, S., Suzuki, T., Oike, Y. & Tomizawa, K., Mar 3 2015, In : Cell Metabolism. 21, 3, p. 428-442 15 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Positron emission tomography to elucidate pharmacokinetic differences of regioisomeric retinoid x receptor agonists

Kobayashi, T., Furusawa, Y., Yamada, S., Akehi, M., Takenaka, F., Sasaki, T., Akahoshi, A., Hanada, T., Matsuura, E., Hirano, H., Tai, A. & Kakuta, H., Mar 12 2015, In : ACS Medicinal Chemistry Letters. 6, 3, p. 334-338 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Possible role of cortactin phosphorylation by protein kinase Cα in actin-bundle formation at growth cone

Yamada, H., Kikuchi, T., Masumoto, T., Wei, F. Y., Abe, T., Takeda, T., Nishiki, T., Tomizawa, K., Watanabe, M., Matsui, H. & Takei, K., Sep 1 2015, In : Biology of the Cell. 107, 9, p. 319-330 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

7-Ketocholesteryl-9-carboxynonanoate enhances ATP binding cassette transporter A1 expression mediated by PPARγ in THP-1 macrophages

Chi, Y., Wang, L., Liu, Y., Ma, Y., Wang, R., Han, X., Qiao, H., Lin, J., Matsuura, E., Liu, S. & Liu, Q., Jun 2014, In : Atherosclerosis. 234, 2, p. 461-468 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cancer stem cells maintain a hierarchy of differentiation by creating their niche

Matsuda, S., Yan, T., Mizutani, A., Sota, T., Hiramoto, Y., Prieto-Vila, M., Chen, L., Satoh, A., Kudoh, T., Kasai, T., Murakami, H., Fu, L., Salomon, D. S. & Seno, M., Jul 1 2014, In : International Journal of Cancer. 135, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived extracellular vesicles

Yan, T., Mizutani, A., Chen, L., Takaki, M., Hiramoto, Y., Matsuda, S., Shigehiro, T., Kasai, T., Kudoh, T., Murakami, H., Masuda, J., Hendrix, M. J. C., Strizzi, L., Salomon, D. S., Fu, L. & Seno, M., 2014, In : Journal of Cancer. 5, 7, p. 572-584 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells

El-Ghlban, S., Kasai, T., Shigehiro, T., Yin, H. X., Sekhar, S., Ida, M., Sanchez, A., Mizutani, A., Kudoh, T., Murakami, H. & Seno, M., 2014, In : BioMed research international. 2014, 152659.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Ectopic calcification: Importance of common nanoparticle scaffolds containing oxidized acidic lipids

Kumon, H., Matsuura, E., Nagaoka, N., Yamamoto, T., Uehara, S., Araki, M., Matsunami, Y., Kobayashi, K. & Matsumoto, A., Feb 2014, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 10, 2, p. 441-450 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Efficient drug delivery of paclitaxel glycoside: A novel solubility gradient encapsulation into liposomes coupled with immunoliposomes preparation

Shigehiro, T., Kasai, T., Murakami, M., Sekhar, S. C., Tominaga, Y., Okada, M., Kudoh, T., Mizutani, A., Murakami, H., Salomon, D. S., Mikuni, K., Mandai, T., Hamada, H. & Seno, M., Sep 29 2014, In : PloS one. 9, 9, e107976.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Efficient transduction of 11 poly-arginine peptide in an ischemic lesion of mouse brain

Gotanda, Y., Wei, F. Y., Harada, H., Ohta, K., Nakamura, K. I., Tomizawa, K. & Ushijima, K., Sep 1 2014, In : Journal of Stroke and Cerebrovascular Diseases. 23, 8, p. 2023-2030 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Estimation of soil-to-plant transfer factors of radiocesium in 99 wild plant species grown in arable lands 1 year after the Fukushima 1 Nuclear Power Plant accident

Yamashita, J., Enomoto, T., Yamada, M., Ono, T., Hanafusa, T., Nagamatsu, T., Sonoda, S. & Yamamoto, Y., Jan 1 2014, In : Journal of Plant Research. 127, 1, p. 11-22 12 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors

Kaitsuka, T., Noguchi, H., Shiraki, N., Kubo, T., Wei, F. Y., Hakim, F., Kume, S. & Tomizawa, K., 2014, In : Stem Cells Translational Medicine. 3, 1, p. 114-127 14 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human

Zhou, B., Wei, F. Y., Kanai, N., Fujimura, A., Kaitsuka, T. & Tomizawa, Z., Sep 2014, In : Human Molecular Genetics. 23, 17, p. 4639-4650 12 p., ddu184.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Inactivation of TRPM7 kinase activity does not impair its channel function in mice

Kaitsuka, T., Katagiri, C., Beesetty, P., Nakamura, K., Hourani, S., Tomizawa, K., Kozak, J. A. & Matsushita, M., Jul 17 2014, In : Scientific reports. 4, 5718.

Research output: Contribution to journalArticle

33 Citations (Scopus)