Neutron Therapy Research Center

Research Output

2005

Oxidized low-density lipoprotein/β2-glycoprotein I complexes and autoantibodies in patients with type 2 diabetes mellitus

Lopez, L. R., Hurley, B. L., Simpson, D. F. & Matsuura, E., 2005, In : Annals of the New York Academy of Sciences. 1051, p. 97-103 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
61 Citations (Scopus)

PDX-1 protein is internalized by lipid raft-dependent macropinocytosis

Noguchi, H., Matsumoto, S., Okitsu, T., Iwanaga, Y., Yonekawa, Y., Nagata, H., Matsushita, M., Wei, F. Y., Matsui, H., Minami, K., Seino, S., Masui, Y., Futaki, S. & Tanaka, K., 2005, In : Cell Transplantation. 14, 9, p. 637-645 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Physiological function of cyclin-dependent kinase 5 in neuron

Wei, F. Y. & Tomizawa, K., May 1 2005, In : Seikagaku. The Journal of Japanese Biochemical Society. 77, 5, p. 436-439 4 p.

Research output: Contribution to journalReview article

Pregnancy loss and endometriosis: Pathogenic role of anti-laminin-1 autoantibodies

Inagaki, J., Kondo, A., Lopez, L. R., Shoenfeld, Y. & Matsuura, E., 2005, In : Annals of the New York Academy of Sciences. 1051, p. 174-184 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Protein transduction technology

Matsushita, M. & Matsui, H., May 2005, In : Journal of Molecular Medicine. 83, 5, p. 324-328 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Quantitative real-time RT-PCR analysis of NY-ESO-1 and LAGE-1a mRNA expression in normal tissues and tumors, and correlation of the protein expression with the mRNA copy number.

Sato, S., Noguchi, Y., Wada, H., Fujita, S., Nakamura, S., Tanaka, R., Nakada, T., Hasegawa, K., Nakagawa, K., Koizumi, F., Ono, T., Nouso, K., Jungbluth, A., Chen, Y. T., Old, L. J., Shiratori, Y. & Nakayama, E., Jan 2005, In : International Journal of Oncology. 26, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Regulation of N-methyl-D-aspartate receptors by calpain in cortical neurons

Wu, H. Y., Yuen, E. Y., Lu, Y. F., Matsushita, M., Matsui, H., Yan, Z. & Tomizawa, K., Jun 3 2005, In : Journal of Biological Chemistry. 280, 22, p. 21588-21593 6 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Regulation of synaptic vesicle recycling by calcineurin in different vesicle pools

Kumashiro, S., Lu, Y. F., Tomizawa, K., Matsushita, M., Wei, F. Y. & Matsui, H., Apr 2005, In : Neuroscience Research. 51, 4, p. 435-443 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Research around β2-glycoprotein I: A major target for antiphospholipid antibodies

Atsumi, T., Amengual, O., Yasuda, S., Matsuura, E. & Koike, T., Aug 2005, In : Autoimmunity. 38, 5, p. 377-381 5 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Significance of valine/leucine247 polymorphism of β2-glycoprotein I in antiphospholipid syndrome: Increased reactivity of anti-β2-glycoprotein I autoantibodies to the valine247 β2-glycoprotein I variant

Yasuda, S., Atsumi, T., Matsuura, E., Kaihara, K., Yamamoto, D., Ichikawa, K. & Koike, T., Jan 2005, In : Arthritis and Rheumatism. 52, 1, p. 212-218 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

The NH2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction

Michiue, H., Tomizawa, K., Wei, F. Y., Matsushita, M., Lu, Y. F., Ichikawa, T., Tamiya, T., Date, I. & Matsui, H., Mar 4 2005, In : Journal of Biological Chemistry. 280, 9, p. 8285-8289 5 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)
34 Citations (Scopus)

Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain

Liu, F., Iqbal-Grundke, I., Iqbal, K., Oda, Y., Tomizawa, K. & Gong, C. X., Nov 11 2005, In : Journal of Biological Chemistry. 280, 45, p. 37755-37762 8 p.

Research output: Contribution to journalArticle

138 Citations (Scopus)

Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells

Michiue, H., Tomizawa, K., Matsushita, M., Tamiya, T., Lu, Y. F., Ichikawa, T., Date, I. & Matsui, H., Jul 18 2005, In : FEBS Letters. 579, 18, p. 3965-3969 5 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

XAGE-1 expression in non-small cell lung cancer and antibody response in patients

Nakagawa, K., Noguchi, Y., Uenaka, A., Sato, S., Okumura, H., Tanaka, M., Shimono, M., Eldib, A. M. A., Ono, T., Ohara, N., Yoshino, T., Yamashita, K., Tsunoda, T., Aoe, M., Shimizu, N. & Nakayama, E., Aug 1 2005, In : Clinical Cancer Research. 11, 15, p. 5496-5503 8 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)
2004

2-Methoxyestradiol enhances p53 protein transduction therapy-associated inhibition of the proliferation of oral cancer cells through the suppression of NFκB activity

Takata, H., Tomizawa, K., Matsushita, M. & Matsui, H., Aug 2004, In : Acta Medica Okayama. 58, 4, p. 181-187 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A-kinase anchoring protein 3 messenger RNA expression in ovarian cancer and its implication on prognosis

Hasegawa, K., Ono, T., Matsushita, H., Shimono, M., Noguchi, Y., Mizutani, Y., Kodama, J., Kudo, T. & Nakayama, E., Jan 1 2004, In : International Journal of Cancer. 108, 1, p. 86-90 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

A new cell-permeable peptide allows successful allogeneic islet transplantation in mice

Noguchi, H., Matsushita, M., Okitsu, T., Moriwaki, A., Tomizawa, K., Kang, S., Li, S. T., Kobayashi, N., Matsumoto, S., Tanaka, K., Tanaka, N. & Matsui, H., Mar 2004, In : Nature Medicine. 10, 3, p. 305-309 5 p.

Research output: Contribution to journalArticle

212 Citations (Scopus)

Anti-laminin-1 autoantibodies, pregnancy loss and endometriosis

Inagaki, J., Kondo, A., Lopez, L. R., Shoenfeld, Y. & Matsuura, E., Sep 2004, In : Clinical and Developmental Immunology. 11, 3-4, p. 261-266 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Are anti-oxidized low-density lipoprotein antibodies pathogenic or protective?

Shoenfeld, Y., Wu, R., Dearing, L. D. & Matsuura, E., Oct 26 2004, In : Circulation. 110, 17, p. 2552-2558 7 p.

Research output: Contribution to journalArticle

126 Citations (Scopus)

Are oxidized LDL/β2-glycoprotein I complexes pathogenic antigens in autoimmune-mediated atherosclerosis?

Matsuura, E. & Lopez, L. R., Jun 2004, In : Clinical and Developmental Immunology. 11, 2, p. 103-111 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
28 Citations (Scopus)

Critical Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration

Wu, H. Y., Tomizawa, K., Oda, Y., Wei, F. Y., Lu, Y. F., Matsushita, M., Li, S. T., Moriwaki, A. & Matsui, H., Feb 6 2004, In : Journal of Biological Chemistry. 279, 6, p. 4929-4940 12 p.

Research output: Contribution to journalArticle

183 Citations (Scopus)

Decreased expression of B7 costimulatory molecules and major histocompatibility complex class-I in human hepatocellular carcinoma

Fujiwara, K., Higashi, T., Nouso, K., Nakatsukasa, H., Kobayashi, Y., Uemura, M., Nakamura, S. I., Sato, S., Hanafusa, T., Yumoto, Y., Naito, I. & Shiratori, Y., 2004, In : Journal of Gastroenterology and Hepatology (Australia). 19, 10, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Exposure of mouse to high gravitation forces induces long-term potentiation in the hippocampus

Ishii, M., Tomizawa, K., Matsushita, M. & Matsui, H., Jun 2004, In : Acta Medica Okayama. 58, 3, p. 143-149 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

HIV-1 Inhibits Long-Term Potentiation and Attenuates Spatial Learning

Li, S. T., Matsushita, M., Moriwaki, A., Saheki, Y., Lu, Y. F., Tomizawa, K., Wu, H. Y., Terada, H. & Matsui, H., Mar 2004, In : Annals of Neurology. 55, 3, p. 362-371 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Immunology of anti-phospholipid antibodies and cofactors

Atsumi, T., Matsuura, E. & Koike, T., May 2004, Systemic Lupus Erythematosus: Fourth Edition. Elsevier Inc., p. 1081-1105 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)

Immunoscreening of a cDNA library from a lung cancer cell line using autologous patient serum: Identification of XAGE-1b as a dominant antigen and its immunogenicity in lung adenocarcinoma

Eldib, A. M. A., Ono, T., Shimono, M., Kaneko, M., Nakagawa, K., Tanaka, R., Noguchi, Y. & Nakayama, E., Feb 4 2004, In : International Journal of Cancer. 108, 4, p. 558-563 6 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Inhibition of RL male 1 tumor growth in BALB/c mice by introduction of the RLakt gene coding for antigen recognized by cytotoxic T-lymphocytes and the GM-CSF gene by in vivo electroporation

Tanaka, M., Yamada, M., Ono, T., Naguchi, Y., Uenaka, A., Ota, S., Hata, H., Harada, M., Tanimoto, M. & Nakayama, E., Feb 2004, In : Cancer Science. 95, 2, p. 154-159 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

NY-ESO-1 expression and immunogenicity in esophageal cancer

Fujita, S., Wada, H., Jungbluth, A. A., Sato, S., Nakata, T., Noguchi, Y., Doki, Y., Yasui, M., Sugita, Y., Yasuda, T., Yano, M., Ono, T., Chen, Y. T., Higashiyama, M., Gnjatic, S., Old, L. J., Nakayama, E. & Monden, M., Oct 1 2004, In : Clinical Cancer Research. 10, 19, p. 6551-6558 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

NY-ESO-1 Expression and Immunogenicity in Malignant and Benign Breast Tumors

Sugita, Y., Wada, H., Fujita, S., Nakata, T., Sato, S., Noguchi, Y., Jungbluth, A. A., Yamaguchi, M., Chen, Y. T., Stockert, E., Gnjatic, S., Williamson, B., Scanlan, M. J., Ono, T., Sakita, I., Yasui, M., Miyoshi, Y., Tamaki, Y., Matsuura, N., Noguchi, S. & 3 others, Old, L. J., Nakayama, E. & Monden, M., Mar 15 2004, In : Cancer Research. 64, 6, p. 2199-2204 6 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Over-Expression of the Testis-Specific Gene TSGA10 in Cancers and Its Immunogenicity

Tanaka, R., Ono, T., Sato, S., Nakada, T., Koizumi, F., Hasegawa, K., Nakagawa, K., Okumura, H., Yamashita, T., Ohtsuka, M., Asagoe, K., Yamasaki, O., Noguchi, Y., Iwatsuki, K. & Nakayama, E., 2004, In : Microbiology and Immunology. 48, 4, p. 339-345 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Oxidized Low-Density Lipoprotein/β2-Glycoprotein I Complexes and Autoantibodies to oxLig-1/β2-Glycoprotein I in Patients with Systemic Lupns Erythematosus and Antiphospholipid Syndrome

Lopez, D., Garcia-Valladares, I., Palafox-Sanchez, C. A., De La Torre, I. G., Kobayashi, K., Matsuura, E. & Lopez, L. R., Mar 2004, In : American Journal of Clinical Pathology. 121, 3, p. 426-436 11 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Photo-acceleration of protein release from endosome in the protein transduction system

Matsushita, M., Noguchi, H., Lu, Y. F., Tomizawa, K., Michiue, H., Li, S. T., Hirose, K., Bonner-Weir, S. & Matsui, H., Aug 13 2004, In : FEBS Letters. 572, 1-3, p. 221-226 6 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Serological identification of endothelial antigens predominantly recognized in Kawasaki disease patients by recombinant expression cloning

Kaneko, M., Ono, T., Matsubara, T., Yamamoto, Y., Ikeda, H., Yoshiki, T., Furukawa, S. & Nakayama, E., 2004, In : Microbiology and Immunology. 48, 9, p. 703-711 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma

Takuma, Y., Nouso, K., Kobayashi, Y., Nakamura, S., Tanaka, H., Matsumoto, E., Fujikawa, T., Suzuki, M., Hanafusa, T. & Shiratori, Y., 2004, In : Journal of Gastroenterology and Hepatology (Australia). 19, 11, p. 1300-1304 5 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

The relationship between peritumoral brain edema and the expression of vascular endothelial growth factor and its receptors in intracranial meningiomas

Otsuka, S., Tamiya, T., Ono, Y., Michiue, H., Kurozumi, K., Daido, S., Kambara, H., Date, I. & Ohmoto, T., Nov 2004, In : Journal of Neuro-Oncology. 70, 3, p. 349-357 9 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2003

An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients

Inagaki, J., Sugiura-Ogasawara, M., Nomizu, M., Nakatsuka, M., Ikuta, K., Suzuki, N., Kaihara, K., Kobayashi, K., Yasuda, T., Shoenfeld, Y., Aoki, K. & Matsuura, E., Mar 1 2003, In : Human Reproduction. 18, 3, p. 544-549 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Anti-idiotypes to oxidized LDL antibodies in intravenous immunoglobulin preparations - Possible immunomodulation of atherosclerosis

Wu, R., Shoenfeld, Y., Sherer, Y., Patnaik, M., Matsuura, E., Gilburd, B., Koike, T. & Peter, J. B., Mar 2003, In : Autoimmunity. 36, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Atherogenic autoantigen: Oxidized LDL complexes with β2-glycoprotein I

Matsuura, E., Kobayashi, K., Koike, T., Shoenfeld, Y., Khamashta, M. A. & Hughes, G. R. V., 2003, In : Immunobiology. 207, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Calcineurin mediates bladder smooth muscle hypertrophy after bladder outlet obstruction

Nozaki, K., Tomizawa, K., Yokoyama, T., Kumon, H. & Matsui, H., Nov 2003, In : Journal of Urology. 170, 5, p. 2077-2081 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Cellular distribution of telomerase reverse transcriptase in human hepatocellular carcinoma

Onishi, T., Nouso, K., Higashi, T., Toshikuni, N., Nakatsukasa, H., Kobayashi, Y., Uemura, M., Yumoto, E., Fujiwara, K., Sato, S., Nakamura, S., Yokoyama, J., Hanafusa, T. & Shiratori, Y., 2003, In : Journal of Gastroenterology and Hepatology (Australia). 18, 10, p. 1168-1174 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Circulating oxidized LDL forms complexes with β 2-glycoprotein I: Implication as an atherogenic autoantigen

Kobayashi, K., Kishi, M., Atsumi, T., Bertolaccini, M. L., Makino, H., Sakairi, N., Yamamoto, I., Yasuda, T., Khamashta, M. A., Hughes, G. R. V., Koike, T., Voelker, D. R. & Matsuura, E., Apr 2003, In : Journal of Lipid Research. 44, 4, p. 716-726 11 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)

Cophosphorylation of amphiphysin I and dynamin I by Cdk5 regulates clathrin-mediated endocytosis of synaptic vesicles

Tomizawa, K., Sunada, S., Lu, Y. F., Oda, Y., Kinuta, M., Ohshima, T., Saito, T., Wei, F. Y., Matsushita, M., Li, S. T., Tsutsui, K., Hisanaga, S. I., Mikoshiba, K., Takei, K. & Matsui, H., Nov 24 2003, In : Journal of Cell Biology. 163, 4, p. 813-824 12 p.

Research output: Contribution to journalArticle

153 Citations (Scopus)

Cryptic CTL epitope on a murine sarcoma Meth A generated by exon extension as a novel mechanism

Uenaka, A., Hirano, Y., Hata, H., Win, S., Aji, T., Tanaka, M., Ono, T., Skipper, J. C. A., Shimizu, K. & Nakayama, E., May 1 2003, In : Journal of Immunology. 170, 9, p. 4862-4868 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Hybridomas expressing γδ T-cell receptors respond to cardiolipin and β2-glycoprotein 1 (apolipoprotein H)

Born, W. K., Vollmer, M., Reardon, C., Matsuura, E., Voelker, D. R., Giclas, P. C. & O'Brien, R. L., Sep 1 2003, In : Scandinavian Journal of Immunology. 58, 3, p. 374-381 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Identification and characterization of mouse SSX genes: A multigene family on the X chromosome with restricted cancer/testis expression

Chen, Y. T., Alpen, B., Ono, T., Gure, A. O., Scanlan, M. A., Biggs, W. H., Arden, K., Nakayama, E. & Old, L. J., Dec 2003, In : Genomics. 82, 6, p. 628-636 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Identification of the antigens predominantly reacted with serum from patients with hepatocellular carcinoma

Uemura, M., Nouso, K., Kobayashi, Y., Tanaka, H., Nakamura, S. I., Higashi, T., Ono, T., Nakayama, E., Hanafusa, T. & Shiratori, Y., May 15 2003, In : Cancer. 97, 10, p. 2474-2479 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
45 Citations (Scopus)