Neutron Therapy Research Center

Research Output

2007

Chronic infections and atherosclerosis

Ayada, K., Yokota, K., Kobayashi, K., Shoenfeld, Y., Matsuura, E. & Oguma, K., Jun 2007, Annals of the New York Academy of Sciences. Vol. 1108. p. 594-602 9 p. (Annals of the New York Academy of Sciences; vol. 1108).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

35 Citations (Scopus)

Colocalization of oxytocin and phosphorylated form of elongation factor 2 in the rat hypothalamus

Fujisawa, T., Moriwaki, A., Matsushita, M., Tomizawa, K. & Matsui, H., Jun 2007, In : Acta Medica Okayama. 61, 3, p. 161-166 6 p.

Research output: Contribution to journalArticle

Cyclin-dependent kinase 5 (cdk5): A potential therapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus

Wei, F. Y. & Tomizawa, K., Oct 1 2007, In : Mini-Reviews in Medicinal Chemistry. 7, 10, p. 1070-1074 5 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Determination of oxidized low-density lipoproteins (ox-LDL) versus ox-LDL/β2GPI complexes for the assessment of autoimmune-mediated atherosclerosis

Lopez, L. R., Buckner, T. R., Hurley, B. L., Kobayashi, K. & Matsuura, E., Aug 2007, Annals of the New York Academy of Sciences. Vol. 1109. p. 303-310 8 p. (Annals of the New York Academy of Sciences; vol. 1109).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

21 Citations (Scopus)

Development of bionanocapsules targeting brain tumors

Tsutsui, Y., Tomizawa, K., Nagita, M., Michiue, H., Nishiki, T., Ohmori, I., Seno, M. & Matsui, H., Sep 26 2007, In : Journal of Controlled Release. 122, 2, p. 159-164 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Distinguished effects of antiphospholipid antibodies and anti-oxidized LDL antibodies on oxidized LDL uptake by macrophages

Kobayashi, K., Tada, K., Itabe, H., Ueno, T., Liu, P. H., Tsutsumi, A., Kuwana, M., Yasuda, T., Shoenfeld, Y., De Groot, P. G. & Matsuura, E., 2007, In : Lupus. 16, 12, p. 929-938 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Elevated serum sFlt-1/Ang-2 ratio in women with preeclampsia

Hirokoshi, K., Maeshima, Y., Kobayashi, K., Matsuura, E., Sugiyama, H., Yamasaki, Y., Masuyama, H., Hiramatsu, Y. & Makino, H., May 2007, In : Nephron - Clinical Practice. 106, 1

Research output: Contribution to journalArticle

24 Citations (Scopus)

Excessive exposure to anionic surfaces maintains autoantibody response to β2-glycoprotein I in patients with antiphospholipid syndrome

Yamaguchi, Y., Seta, N., Kaburaki, J., Kobayashi, K., Matsuura, E. & Kuwana, M., Dec 15 2007, In : Blood. 110, 13, p. 4312-4318 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Inhibitory effect of polyunsaturated fatty acids on apoptosis induced by etoposide, okadaic acid and AraC in Neuro2a cells

Wu, Y., Tada, M., Takahata, K., Tomizawa, K. & Matsui, H., Jun 2007, In : Acta Medica Okayama. 61, 3, p. 147-152 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
44 Citations (Scopus)

Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis

Liang, S., Wei, F. Y., Wu, Y. M., Tanabe, K., Abe, T., Oda, Y., Yoshida, Y., Yamada, H., Matsui, H., Tomizawa, K. & Takei, K., Sep 2007, In : Journal of Neurochemistry. 102, 5, p. 1466-1476 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Novel protein transduction method by using 11R: An effective new drug delivery system for the treatment of cerebrovascular diseases

Ogawa, T., Ono, S., Ichikawa, T., Arimitsu, S., Onoda, K., Tokunaga, K., Sugiu, K., Tomizawa, K., Matsui, H. & Date, I., Apr 2007, In : Stroke. 38, 4, p. 1354-1361 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Postinfectious immunodeficiency and autoimmunity: Pathogenic and clinical values and implications

Khitrov, A. N., Shogenov, Z. S., Tretyak, E. B., Ischenko, A. I., Matsuura, E., Neuhaus, O., Paltsev, M. A. & Suchkov, S. V., May 2007, In : Expert Review of Clinical Immunology. 3, 3, p. 323-331 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Subclinical atherosclerosis in primary antiphospholipid syndrome

Margarita, A., Batuca, J., Scenna, G., Alves, J. D., Lopez, L., Iannaccone, L., Matsuura, E. & Ames, P. R. J., Jun 2007, Annals of the New York Academy of Sciences. Vol. 1108. p. 475-480 6 p. (Annals of the New York Academy of Sciences; vol. 1108).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

28 Citations (Scopus)

The association of C-reactive protein with an oxidative metabolite of LDL and its implication in atherosclerosis

Tabuchi, M., Inoue, K., Kataoka, H., Kobayashi, K., Teramoto, M., Takasugi, K., Shikata, K., Yamamura, M., Ando, K., Nishida, K., Kasahara, J., Kume, N., Lopez, L. R., Mitsudo, K., Nobuyoshi, M., Yasuda, T., Kita, T., Makino, H. & Matsuura, E., Apr 2007, In : Journal of Lipid Research. 48, 4, p. 768-781 14 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation

Wu, Y., Liang, S., Oda, Y., Ohmori, I., Nishiki, T., Takei, K., Matsui, H. & Tomizawa, K., Jun 20 2007, In : EMBO Journal. 26, 12, p. 2981-2990 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

β2-Glycoprotein I autoantibodies

Matsuura, E., Dier, K. J. & Lopez, L. R., 2007, Autoantibodies. Elsevier Inc., p. 687-693 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)
2006

Accelerated Atheroma in the Antiphospholipid Syndrome

Matsuura, E., Kobayashi, K., Tabuchi, M. & Lopez, L. R., Aug 2006, In : Rheumatic Disease Clinics of North America. 32, 3, p. 537-551 15 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A cell-permeable NFAT inhibitor peptide prevents pressure-overload cardiac hypertrophy

Kuriyama, M., Matsushita, M., Tateishi, A., Moriwaki, A., Tomizawa, K., Ishino, K., Sano, S. & Matsui, H., Mar 2006, In : Chemical Biology and Drug Design. 67, 3, p. 238-243 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Antibodies against β2-glycoprotein I complexed with an oxidised lipoprotein relate to intima thickening of carotid arteries in primary antiphospholipid syndrome

Ames, P. R. J., Delgado Alves, J., Lopez, L. R., Gentile, F., Margarita, A., Pizzella, L., Batuca, J., Scenna, G., Brancaccio, V. & Matsuura, E., Mar 1 2006, In : Clinical and Developmental Immunology. 13, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
21 Citations (Scopus)

Expression and immunogenicity of NY-ESO-1 in hepatocellular carcinoma

Nakamura, S., Nouso, K., Noguchi, Y., Higashi, T., Ono, T., Jungbluth, A., Chen, Y. T., Old, L. J., Nakayama, E. & Shiratori, Y., 2006, In : Journal of Gastroenterology and Hepatology (Australia). 21, 8, p. 1281-1285 5 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Immunosuppression for islet transplantation

Noguchi, H., Matsumoto, S., Matsushita, M., Kobayashi, N., Tanaka, K., Matsui, H. & Tanaka, N., Apr 2006, In : Acta Medica Okayama. 60, 2, p. 71-76 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Induction of defense responses in pea tissues by inorganic phosphate

Kawahara, T., Namba, H., Toyoda, K., Kasai, T., Sugimoto, M., Inagaki, Y., Ichinose, Y. & Shiraishi, T., Jun 2006, In : Journal of General Plant Pathology. 72, 3, p. 129-136 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Oxidative modification of low-density lipoprotein and immune regulation of atherosclerosis

Matsuura, E., Kobayashi, K., Tabuchi, M. & Lopez, L. R., Nov 2006, In : Progress in Lipid Research. 45, 6, p. 466-486 21 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Oxidized low-density lipoprotein and β2-glycoprotein I in patients with systemic lupus erythematosus and increased carotid intima-media thickness: Implications in autoimmune-mediated atherosclerosis

Lopez, L. R., Salazar-Paramo, M., Palafox-Sanchez, C., Hurley, B. L., Matsuura, E. & Garcia-De La Torre, I., 2006, In : Lupus. 15, 2, p. 80-86 7 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

OY-TES-1 expression and serum immunoreactivity in epithelial ovarian cancer

Tammela, J., Uenaka, A., Ono, T., Noguchi, Y., Jungbluth, A. A., Mhawech-Fauceglia, P., Qian, F., Schneider, S., Sharma, S., Driscoll, D., Lele, S., Old, L. J., Nakayama, E. & Odunsi, K., Oct 2006, In : International Journal of Oncology. 29, 4, p. 903-910 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

p53 protein transduction therapy: Successful targeting and inhibition of the growth of the bladder cancer cells

Inoue, M., Tomizawa, K., Matsushita, M., Lu, Y. F., Yokoyama, T., Yanai, H., Takashima, A., Kumon, H. & Matsui, H., Jan 2006, In : European Urology. 49, 1, p. 161-168 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Pea extracellular Cu/Zn-superoxide dismutase responsive to signal molecules from a fungal pathogen

Kasai, T., Suzuki, T., Ono, K., Ogawa, KI., Inagaki, Y., Ichinose, Y., Toyoda, K. & Shiraishi, T., Oct 2006, In : Journal of General Plant Pathology. 72, 5, p. 265-272 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2005

Accelerated atherosclerosis in autoimmune rheumatic diseases

Shoenfeld, Y., Gerli, R., Doria, A., Matsuura, E., Cerinic, M. M., Ronda, N., Jara, L. J., Abu-Shakra, M., Meroni, P. L. & Sherer, Y., Nov 2005, In : Circulation. 112, 21, p. 3337-3347 11 p.

Research output: Contribution to journalArticle

427 Citations (Scopus)

Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma

Uematsu, S., Higashi, T., Nouso, K., Kariyama, K., Nakamura, S. I., Suzuki, M., Nakatsukasa, H., Kobayashi, Y., Hanafusa, T., Tsuji, T. & Shiratori, Y., 2005, In : Journal of Gastroenterology and Hepatology (Australia). 20, 4, p. 583-588 6 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

A new approach to inhibiting astrocytic IP3-induced intracellular calcium increase in an astrocyte-neuron co-culture system

Saheki, Y., Li, S. T., Matsushita, M., Wu, Y. M., Cai, W. H., Wei, F. Y., Lu, Y. F., Moriwaki, A., Tomizawa, K. & Matsui, H., Sep 7 2005, In : Brain Research. 1055, 1-2, p. 196-201 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Antigenic structures recognized by anti-β2-glycoprotein I auto-antibodies

Kasahara, H., Matsuura, E., Kaihara, K., Yamamoto, D., Kobayashi, K., Inagaki, J., Ichikawa, K., Tsutsumi, A., Yasuda, S., Atsumi, T., Yasuda, T. & Koike, T., Dec 2005, In : International Immunology. 17, 12, p. 1533-1542 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Calpain inhibitors prevent neuronal cell death and ameliorate motor disturbances after compression-induced spinal cord injury in rats

Arataki, S., Tomizawa, K., Moriwaki, A., Nishida, K., Matsushita, M., Ozaki, T., Kunisada, T., Yoshida, A., Inoue, H. & Matsui, H., Mar 2005, In : Journal of Neurotrauma. 22, 3, p. 398-406 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Cdk5-dependent regulation of glucose-stimulated insulin secretion

Wei, F. Y., Nagashima, K., Ohshima, T., Saheki, Y., Lu, Y. F., Matsushita, M., Yamada, Y., Mikoshiba, K., Seino, Y., Matsui, H. & Tomizawa, K., Oct 2005, In : Nature Medicine. 11, 10, p. 1104-1108 5 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPMT/ChaK1

Matsushita, M., Kozak, J. A., Shimizu, Y., McLachlin, D. T., Yamaguchi, H., Wei, F. Y., Tomizawa, K., Matsui, H., Chait, B. T., Cahalan, M. D. & Nairn, A. C., May 27 2005, In : Journal of Biological Chemistry. 280, 21, p. 20793-20803 11 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

Characterization of a murine anti-laminin-1 monoclonal antibody (AK8) produced by immunization with mouse-derived laminin-1

Kondo, A., Inagaki, J., Kobayashi, K., Tsukamoto, H., Yamamoto, D., Nakatsuka, M., Suzuki, N., Nomizu, M., Amano, S., Matsubayashi, H., Yasuda, T., Lopez, L. R., Shoenfeld, Y., Makino, T. & Matsuura, E., Mar 2005, In : Clinical and Developmental Immunology. 12, 1, p. 67-73 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability

Wei, F. Y., Tomizawa, K., Ohshima, T., Asada, A., Saito, T., Nguyen, C., Bibb, J. A., Ishiguro, K., Kulkarni, A. B., Pant, H. C., Mikoshiba, K., Matsui, H. & Hisanaga, S. I., Apr 2005, In : Journal of Neurochemistry. 93, 2, p. 502-512 11 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2 Citations (Scopus)

From animal models to human genetics: Research on the induction and pathogenicity of autoantibodies

Conrad, K., Bachmann, M. P., Matsuura, E. & Shoenfeld, Y., Mar 2005, In : Autoimmunity Reviews. 4, 3, p. 178-187 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation

Hanafusa, T., Shinji, T., Shiraha, H., Nouso, K., Iwasaki, Y., Yumoto, E., Ono, T. & Koide, N., Jan 20 2005, In : BMC Cancer. 5, 9.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Identification of an HLA-A24-restricted OY-TES-1 epitope recognized by cytotoxic T-cells

Okumura, H., Noguchi, Y., Uenaka, A., Aji, T., Ono, T., Nakagawa, K., Aoe, M., Shimizu, N. & Nakayama, E., 2005, In : Microbiology and Immunology. 49, 11, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Identification of glioma-specific RFX4-E and -F isoforms and humoral immune response in patients

Matsushita, H., Uenaka, A., Ono, T., Hasegawa, K., Sato, S., Koizumi, F., Nakagawa, K., Toda, M., Shingo, T., Ichikawa, T., Noguchi, Y., Tamiya, T., Furuta, T., Kawase, T., Date, I. & Nakayama, E., Nov 2005, In : Cancer Science. 96, 11, p. 801-809 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

IGFBP-3 expression in hepatocellular carcinoma involves abnormalities in TGF-ß and/or Rb signaling pathways

Yumoto, E., Nakatsukasa, H., Hanafusa, T., Yumoto, Y., Nouso, K., Matsumoto, E., Onishi, T., Takuma, Y., Tanaka, H., Fujikawa, T., Suzuki, M., Uemura, M. & Shiratori, Y., Nov 2005, In : International Journal of Oncology. 27, 5, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Impairment of hippocampal long-term depression and defective spatial learning and memory in p35-/- mice

Ohshima, T., Ogura, H., Tomizawa, K., Hayashi, K., Suzuki, H., Saito, T., Kamei, H., Nishi, A., Bibb, J. A., Hisanaga, S. I., Matsui, H. & Mikoshiba, K., Aug 2005, In : Journal of Neurochemistry. 94, 4, p. 917-925 9 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Increase of serum angiopoietin-2 during pregnancy is suppressed in women with preeclampsia

Hirokoshi, K., Maeshima, Y., Kobayashi, K., Matsuura, E., Sugiyama, H., Yamasaki, Y., Masuyama, H., Hiramatsu, Y. & Makino, H., Sep 2005, In : American Journal of Hypertension. 18, 9, p. 1181-1188 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Intravenous immunoglobulin and atherosclerosis

Matsuura, E., Kobayashi, K., Inoue, K. & Shoenfeld, Y., Dec 2005, In : Clinical Reviews in Allergy and Immunology. 29, 3, p. 311-320 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Lymphocyte subpopulations and intima media thickness in primary antiphospholipd syndrome

Ames, P. R. J., Tommasino, C., Fossati, G., Matsuura, E., Margarita, A., Saulino, A., Lopez, L., Scenna, G. & Brancaccio, V., 2005, In : Lupus. 14, 10, p. 809-813 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Mechanism of PDX-1 protein transduction

Noguchi, H., Matsushita, M., Matsumoto, S., Lu, Y. F., Matsui, H. & Bonner-Weir, S., Jun 24 2005, In : Biochemical and Biophysical Research Communications. 332, 1, p. 68-74 7 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Oxidized LDL/β2-glycoprotein I complexes: New aspects in atherosclerosis

Matsuura, E., Kobayashi, K., Inoue, K., Lopez, L. R. & Shoenfeld, Y., 2005, In : Lupus. 14, 9, p. 736-741 6 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)