Neutron Therapy Research Center

Research Output

2013

Bimodal anti-glioma mechanisms of cilengitide demonstrated by novel invasive glioma models

Onishi, M., Ichikawa, T., Kurozumi, K., Fujii, K., Yoshida, K., Inoue, S., Michiue, H., Chiocca, E. A., Kaur, B. & Date, I., Apr 2013, In : Neuropathology. 33, 2, p. 162-174 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

CACNA1A variants may modify the epileptic phenotype of Dravet syndrome

Ohmori, I., Oouchida, M., Kobayashi, K., Jitsumori, Y., Mori, A., Michiue, H., Nishiki, T., Ohtsuka, Y. & Matsui, H., Feb 2013, In : Neurobiology of Disease. 50, 1, p. 209-217 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics

Fujimura, A., Michiue, H., Cheng, Y., Uneda, A., Tani, Y., Nishiki, T., Ichikawa, T., Wei, F. Y., Tomizawa, K. & Matsui, H., Nov 2013, In : Neoplasia (United States). 15, 11, p. 1272-1281 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Gene expression profiling of the anti-glioma effect of Cilengitide

Onishi, M., Kurozumi, K., Ichikawa, T., Michiue, H., Fujii, K., Ishida, J., Shimazu, Y., Chiocca, E. A., Kaur, B. & Date, I., 2013, In : SpringerPlus. 2, 1

Research output: Contribution to journalArticle

10 Citations (Scopus)

Inhalation of 10% carbon dioxide rapidly terminates Scn1a mutation-related hyperthermia-induced seizures

Ohmori, I., Hayashi, K., Wang, H., Oouchida, M., Fujita, N., Inoue, T., Michiue, H., Nishiki, T. & Matsui, H., Jul 2013, In : Epilepsy Research. 105, 1-2, p. 220-224 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Laminin-1 (LM-111) in preeclampsia and systemic lupus erythematosus

Páez, M. C., Matsuura, E., Díaz, L. A., Shoenfeld, Y., Serrano, N. C. & Anaya, J. M., Feb 2013, In : Autoimmunity. 46, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Some aspects of air-entrainment on decay rates in hydraulic pulse tests

Selvadurai, A. P. S. & Ichikawa, Y., Oct 24 2013, In : Engineering Geology. 165, p. 38-45 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Stabilization of actin bundles by a Dynamin 1/cortactin ring complex is necessary for growth cone filopodia

Yamada, H., Abe, T., Satoh, A., Okazaki, N., Tago, S., Kobayashi, K., Yoshida, Y., Oda, Y., Watanabe, M., Tomizawa, K., Matsui, H. & Takei, K., Mar 6 2013, In : Journal of Neuroscience. 33, 10, p. 4514-4526 13 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Surgical and endovascular treatment for superior cerebellar artery aneurysms: Report of two cases

Haruma, J., Sugiu, K., Shimazu, Y., Michiue, H., Tokunaga, K. & Date, I., Jan 2013, In : Neurological Surgery. 41, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

β2-Glycoprotein I Autoantibodies

Matsuura, E. & Lopez, L. R., Dec 2013, Autoantibodies: Third Edition. Elsevier B.V., p. 689-698 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Analysis of the permeability characteristics along rough-walled fractures using a homogenization method

Chae, B. G., Choi, J. H., Ichikawa, Y. & Seo, Y. S., Feb 2012, In : Nuclear Engineering and Technology. 44, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Antidepressant-like effect of sildenafil through oxytocin-dependent cyclic AMP response element-binding protein phosphorylation

Matsushita, H., Matsuzaki, M., Han, X. J., Nishiki, T., Ohmori, I., Michiue, H., Matsui, H. & Tomizawa, K., Jan 3 2012, In : Neuroscience. 200, p. 13-18 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors into cell nuclei

Hitsuda, T., Michiue, H., Kitamatsu, M., Fujimura, A., Wang, F., Yamamoto, T., Han, X. J., Tazawa, H., Uneda, A., Ohmori, I., Nishiki, T., Tomizawa, K. & Matsui, H., Jun 2012, In : Biomaterials. 33, 18, p. 4665-4672 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Aspirin insensitive thromboxane generation is associated with oxidative stress in type 2 diabetes mellitus

Ames, P. R. J., Batuca, J. R., Muncy, I. J., De La Torre, I. G., Pascoe-Gonzales, S., Guyer, K., Matsuura, E. & Lopez, L. R., Sep 2012, In : Thrombosis Research. 130, 3, p. 350-354 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Ca 2+-independent syntaxin binding to the C 2B effector region of synaptotagmin

Masumoto, T., Suzuki, K., Ohmori, I., Michiue, H., Tomizawa, K., Fujimura, A., Nishiki, T. & Matsui, H., Jan 2012, In : Molecular and Cellular Neuroscience. 49, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery

Candan, G., Michiue, H., Ishikawa, S., Fujimura, A., Hayashi, K., Uneda, A., Mori, A., Ohmori, I., Nishiki, T., Matsui, H. & Tomizawa, K., Sep 2012, In : Biomaterials. 33, 27, p. 6468-6475 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Induction of autophagic cell death of glioma-initiating cells by cell-penetrating d-isomer peptides consisting of Pas and the p53 C-terminus

Ueda, Y., Wei, F. Y., Hide, T. I., Michiue, H., Takayama, K., Kaitsuka, T., Nakamura, H., Makino, K., Kuratsu, J. I., Futaki, S. & Tomizawa, K., Dec 2012, In : Biomaterials. 33, 35, p. 9061-9069 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

On aspirin treatment but not baseline thromboxane B2 levels predict adverse outcomes in patients with acute coronary syndromes

Matsuura, E., Guyer, K., Yamamoto, H., Lopez, L. R. & Inoue, K., Sep 2012, In : Journal of Thrombosis and Haemostasis. 10, 9, p. 1949-1951 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Oxytocin: A therapeutic target for mental disorders

Matsuzaki, M., Matsushita, H., Tomizawa, K. & Matsui, H., Nov 2012, In : Journal of Physiological Sciences. 62, 6, p. 441-444 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
4 Citations (Scopus)

RGS2 mediates the anxiolytic effect of oxytocin

Okimoto, N., Bosch, O. J., Slattery, D. A., Pflaum, K., Matsushita, H., Wei, F. Y., Ohmori, M., Nishiki, T., Ohmori, I., Hiramatsu, Y., Matsui, H., Neumann, I. D. & Tomizawa, K., May 9 2012, In : Brain Research. 1453, p. 26-33 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Serological identification of Tektin5 as a cancer/testis antigen and its immunogenicity

Hanafusa, T., Mohamed, A. E. A., Domae, S., Nakayama, E. & Ono, T., Nov 14 2012, In : BMC Cancer. 12, 520.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Transport phenomena in porous media: Aspects of micro/macro behaviour

Ichikawa, Y. & Selvadurai, A. P. S., May 1 2012, Springer-Verlag Berlin Heidelberg. 383 p.

Research output: Book/ReportBook

38 Citations (Scopus)

β2-glycoprotein I and oxidative inflammation in early atherogenesis: A progression from innate to adaptive immunity?

Matsuura, E., Lopez, L. R., Shoenfeld, Y. & Ames, P. R. J., Dec 2012, In : Autoimmunity Reviews. 12, 2, p. 241-249 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2011

An assessment of radioactivity levels of 210Pb and 40K in tobacco and radiation exposure from smoking

Nagamatsu, T., Sakoda, A., Kataoka, T., Ono, T. & Yamaoka, K., 2011, In : Acta Medica Okayama. 65, 2, p. 91-95 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A Possible mechanism of autoimmune-mediated infertility in women with endometriosis

Inagaki, J., Hao, L., Nakatsuka, M., Yasuda, T., Hiramatsu, Y., Shoenfeld, Y. & Matsuura, E., Aug 2011, In : American Journal of Reproductive Immunology. 66, 2, p. 90-99 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice

Wei, F. Y., Suzuki, T., Watanabe, S., Kimura, S., Kaitsuka, T., Fujimura, A., Matsui, H., Atta, M., Michiue, H., Fontecave, M., Yamagata, K., Suzuki, T. & Tomizawa, K., Sep 1 2011, In : Journal of Clinical Investigation. 121, 9, p. 3598-3608 11 p.

Research output: Contribution to journalArticle

132 Citations (Scopus)

Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma

Kubo, T., Toyooka, S., Tsukuda, K., Sakaguchi, M., Fukazawa, T., Sou, J., Asano, H., Ueno, T., Muraoka, T., Yamamoto, H., Nasu, Y., Kishimoto, T., Pass, H. I., Matsui, H., Huh, N. H. & Miyoshi, S., Aug 1 2011, In : Clinical Cancer Research. 17, 15, p. 4965-4974 10 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Expression of a constitutively active calcineurin encoded by an intron-retaining mRNA in follicular keratinocytes

Fujimura, A., Michiue, H., Nishiki, T., Ohmori, I., Wei, F. Y., Matsui, H. & Tomizawa, K., 2011, In : PLoS One. 6, 3, e17685.

Research output: Contribution to journalArticle

7 Citations (Scopus)

In vivo oxidation, platelet activation and simultaneous occurrence of natural immunity in atherosclerosis-prone mice

Shen, L., Matsunami, Y., Quan, N., Kobayashi, K., Matsuura, E. & Oguma, K., May 2011, In : Israel Medical Association Journal. 13, 5, p. 278-283 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Isolation and characterization of human lung cancer antigens by serological screening with autologous antibodies

Hanafusa, T., Mohamed, A. E. A., Kitaoka, K., Ohue, Y., Nakayama, E. & Ono, T., Feb 1 2011, In : Cancer Letters. 301, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Nanoparticle-based drug delivery systems for solid brain tumors

Feng, B., Matsui, H. & Tomizawa, K., 2011, In : Current Nanoscience. 7, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Protein Delivery

Han, X. J. & Tomizawa, K., Oct 25 2011, Primary and Stem Cells: Gene Transfer Technologies and Applications. John Wiley and Sons, p. 119-133 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein therapy using heme-oxygenase-1 fused to a polyarginine transduction domain attenuates cerebral vasospasm after experimental subarachnoid hemorrhage

Ogawa, T., Hänggi, D., Wu, Y., Michiue, H., Tomizawa, K., Ono, S., Matsui, H., Date, I. & Steiger, H. J., Nov 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 11, p. 2231-2242 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Recombinant domain v of β2-glycoprotein i inhibits the formation of a 7-ketocholesteryl-9-carboxynonanoate and β2- glycoprotein i complex

Zhang, Y., Li, W., Chi, Y., Wang, R., Wang, D., Zhang, F., Liu, Z., Matsuura, E. & Liu, Q., Jan 2011, In : Journal of Biochemistry. 149, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Regulation of mitochondrial dynamics and neurodegenerative diseases

Han, X. J., Tomizawa, K., Fujimura, A., Ohmori, I., Nishiki, T., Matsushita, M. & Matsui, H., Feb 22 2011, In : Acta Medica Okayama. 65, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Therapy for hyperthermia-induced seizures in Scn1a mutant rats

Hayashi, K., Ueshima, S., Oouchida, M., Mashimo, T., Nishiki, T., Sendo, T., Serikawa, T., Matsui, H. & Ohmori, I., May 2011, In : Epilepsia. 52, 5, p. 1010-1017 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Transdifferentiation of glioblastoma cells into vascular endothelial cells

Soda, Y., Marumoto, T., Friedmann-Morvinski, D., Soda, M., Liu, F., Michiue, H., Pastorino, S., Yang, M., Hoffman, R. M., Kesari, S. & Verma, I. M., Mar 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 11, p. 4274-4280 7 p.

Research output: Contribution to journalArticle

309 Citations (Scopus)
2010

7-Ketocholesterol induces cell apoptosis by activation of nuclear factor kappa B in mouse macrophages

Huang, Z., Liu, Q., Li, W., Wang, R., Wang, D., Zhang, Y., Zhang, F., Chi, Y., Liu, Z., Matsuura, E., Liuc, Z. & Zhang, Q., Apr 2010, In : Acta Medica Okayama. 64, 2, p. 85-93 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

7-Ketocholesteryl-9-carboxynonanoate induced nuclear factor-kappa B activation in J774A.1 macrophages

Huang, Z., Li, W., Wang, R., Zhang, F., Chi, Y., Wang, D., Liu, Z., Zhang, Y., Matsuura, E. & Liu, Q., Nov 20 2010, In : Life Sciences. 87, 19-22, p. 651-657 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A new development of coupled diffusion, seepage and consolidation problem of multi-component mixture in saturated porous media

Ichikawa, Y., Tachibana, S., Choi, J. H. & Selvadurai, A. P. S., Mar 2010, In : Zairyo/Journal of the Society of Materials Science, Japan. 59, 3, p. 227-230 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cell-penetrating d-Isomer Peptides of p53 C-terminus: Long-term Inhibitory Effect on the Growth of Bladder Cancer

Araki, D., Takayama, K., Inoue, M., Watanabe, T., Kumon, H., Futaki, S., Matsui, H. & Tomizawa, K., Apr 2010, In : Urology. 75, 4, p. 813-819 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Development of a bifunctional immunoliposome system for combined drug delivery and imaging in vivo

Feng, B., Tomizawa, K., Michiue, H., Han, X. J., Miyatake, S. I. & Matsui, H., May 2010, In : Biomaterials. 31, 14, p. 4139-4145 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Effect of inhibition of glycogen synthase kinase-3 on cardiac hypertrophy during acute pressure overload

Tateishi, A., Matsushita, M., Asai, T., Masuda, Z., Kuriyama, M., Kanki, K., Ishino, K., Kawada, M., Sano, S. & Matsui, H., 2010, In : General Thoracic and Cardiovascular Surgery. 58, 6, p. 265-270 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Genetic seizure susceptibility underlying acute encephalopathies in childhood

Kobayashi, K., Oouchida, M., Okumura, A., Maegaki, Y., Nishiyama, I., Matsui, H., Ohtsuka, Y. & Ohmori, I., Oct 2010, In : Epilepsy Research. 91, 2-3, p. 143-152 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

High-density lipoprotein inversely relates to its specific autoantibody favoring oxidation in thrombotic primary antiphospholipid syndrome

Ames, P. R. J., Matsuura, E., Batuca, J. R., Ciampa, A., Lopez, L. L., Ferrara, F., Iannaccone, L. & Delgado Alves, J., May 2010, In : Lupus. 19, 6, p. 711-716 6 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Oxidized-LDL/β2-glycoprotein I complexes are associated with disease severity and increased risk for adverse outcomes in patients with acute coronary syndromes

Greco, T. P., Conti-Kelly, A. M., Anthony, J. R., Greco, T., Doyle, R., Boisen, M., Kojima, K., Matsuura, E. & Lopez, L. R., May 2010, In : American Journal of Clinical Pathology. 133, 5, p. 737-743 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Oxytocin mediates the antidepressant effects of mating behavior in male mice

Matsushita, H., Tomizawa, K., Okimoto, N., Nishiki, T., Ohmori, I. & Matsui, H., Oct 2010, In : Neuroscience Research. 68, 2, p. 151-153 3 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Pathophysiology of β2-glycoprotein i in antiphospholipid syndrome

Matsuura, E., Shen, L., Matsunami, Y., Quan, N., Makarova, M., Geske, F. J., Boisen, M., Yasuda, S., Kobayashi, K. & Lopez, L. R., Apr 2010, In : Lupus. 19, 4, p. 379-384 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Plasma membrane-localized transporter for aluminum in rice

Xia, J., Yamaji, N., Kasai, T. & Ma, J. F., Oct 26 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 43, p. 18381-18385 5 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)