Neutron Therapy Research Center

Research Output

2020

Conditional generative adversarial networks to model iPSC-derived cancer stem cells

Aida, S., Kameda, H., Nishisako, S., Kasai, T., Sato, A. & Sugiyama, T., Jan 1 2020, In : Journal of Advanced Computational Intelligence and Intelligent Informatics. 24, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

Sera anti-p53 antibody provides new information which explains the link between diabetes and cancer

Sauriasari, R., Sekar, A. P., Aisyah, N., Syahdi, R. R. & Matsuura, E., Jan 1 2020, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 13, p. 325-331 7 p.

Research output: Contribution to journalArticle

Open Access
2019

A culture substratum with net-like polyamide fibers promotes the differentiation of mouse and human pluripotent stem cells to insulin-producing cells

Kaitsuka, T., Kojima, R., Kawabe, M., Noguchi, H., Shiraki, N., Kume, S. & Tomizawa, K., Jun 19 2019, In : Biomedical materials (Bristol, England). 14, 4, 1 p.

Research output: Contribution to journalArticle

A leucine zipper-based peptide hybrid delivers functional Nanog protein inside the cell nucleus

Hakata, Y., Michiue, H., Ohtsuki, T., Miyazawa, M. & Kitamatsu, M., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Mutants of β2-glycoprotein I: Their features and potent applications

Shen, L., Azmi, N. U., Tan, X. W., Yasuda, S., Wahyuningsih, A. T., Inagaki, J., Kobayashi, K., Ando, E., Sasaki, T. & Matsuura, E., Jan 1 2019, In : Best Practice and Research: Clinical Rheumatology.

Research output: Contribution to journalReview article

Novel single-chain variant of antibody against mesothelin established by phage library

Yakushiji, H., Kobayashi, K., Takenaka, F., Kishi, Y., Shinohara, M., Akehi, M., Sasaki, T., Ohno, E. & Matsuura, E., Sep 1 2019, In : Cancer Science. 110, 9, p. 2722-2733 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Oxytocin and Stress: Neural Mechanisms, Stress-Related Disorders, and Therapeutic Approaches

Matsushita, H., Latt, H. M., Koga, Y., Nishiki, T. & Matsui, H., Oct 1 2019, In : Neuroscience. 417, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Use of DNA-generated gold nanoparticles to radiosensitize and eradicate radioresistant glioma stem cells

Kunoh, T., Shimura, T., Kasai, T., Matsumoto, S., Mahmud, H., Khayrani, A. C., Seno, M., Kunoh, H. & Takada, J., Feb 1 2019, In : Nanotechnology. 30, 5, 055101.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2018

Boron Neutron Capture Therapy Combined with Early Successive Bevacizumab Treatments for Recurrent Malignant Gliomas - A Pilot Study

Shiba, H., Takeuchi, K., Hiramatsu, R., Furuse, M., Nonoguchi, N., Kawabata, S., Kuroiwa, T., Kondo, N., Sakurai, Y., Suzuki, M., Ono, K., Oue, S., Ishikawa, E., Michiue, H. & Miyatake, S. I., Dec 15 2018, In : Neurologia Medico-Chirurgica. 58, 12, p. 487-494 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion

Otani, Y., Ichikawa, T., Kurozumi, K., Inoue, S., Ishida, J., Oka, T., Shimizu, T., Tomita, Y., Hattori, Y., Uneda, A., Matsumoto, Y., Michiue, H. & Date, I., Feb 8 2018, In : Oncogene. 37, 6, p. 777-786 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Oxytocin Inhibits Corticosterone-induced Apoptosis in Primary Hippocampal Neurons

Latt, H. M., Matsushita, H., Morino, M., Koga, Y., Michiue, H., Nishiki, T., Tomizawa, K. & Matsui, H., May 21 2018, In : Neuroscience. 379, p. 383-389 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Physical modification of carbon nanotubes with a dendrimer bearing terminal mercaptoundecahydrododecaborates (Na2B12H11S)

Yamagami, M., Tajima, T., Ishimoto, K., Miyake, H., Michiue, H. & Takaguchi, Y., Jan 1 2018, (Accepted/In press) In : Heteroatom Chemistry. e21467.

Research output: Contribution to journalArticle

Regulation of mitochondrial iron homeostasis by sideroflexin 2

Mon, E. E., Wei, F. Y., Ahmad, R. N. R., Yamamoto, T., Moroishi, T. & Tomizawa, K., Jan 1 2018, (Accepted/In press) In : Journal of Physiological Sciences.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Suppression effect on IFN-γ of adipose tissue-derived mesenchymal stem cells isolated from β2-microglobulin-deficient mice

Masuda, J., Takayama, E., Ichinohe, T., Strober, W., Mizuno-Kamiya, M., Ikawa, T., Kitani, A., Kawaki, H., Fuss, I., Kawamoto, H., Seno, A., Vaidyanath, A., Umemura, N., Mizutani, A., Kasai, T., Honjo, Y., Satoh, A., Murakami, H., Katsura, Y., Kondoh, N. & 1 others, Seno, M., Nov 1 2018, In : Experimental and Therapeutic Medicine. 16, 5, p. 4277-4282 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice

Watanabe, H., Watanabe, K. S., Liu, K., Hiramatsu, S., Zeggar, S., Katsuyama, E., Tatebe, N., Akahoshi, A., Takenaka, F., Hanada, T., Akehi, M., Sasaki, T., Sada, K., Matsuura, E., Nishibori, M. & Wada, J., Sep 15 2017, In : Molecular Therapy - Methods and Clinical Development. 6, p. 31-39 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

In vitro analysis of radioprotective effect of monoterpenes

Kudo, K. I., Hanafusa, T. & Ono, T., May 4 2017, (Accepted/In press) In : Journal of Radioanalytical and Nuclear Chemistry. p. 1-6 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

PIK3R1Met326Ile germline mutation correlates with cysteine-rich protein 61 expression and poor prognosis in glioblastoma

Otani, Y., Ishida, J., Kurozumi, K., Oka, T., Shimizu, T., Tomita, Y., Hattori, Y., Uneda, A., Matsumoto, Y., Michiue, H., Tomida, S., Matsubara, T., Ichikawa, T. & Date, I., Dec 1 2017, In : Scientific Reports. 7, 1, 7391.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ

Li, J., Xiu, Z., Wang, R., Yu, C., Chi, Y., Qin, J., Fu, C., Matsuura, E. & Liu, Q., May 15 2017, In : Life Sciences. 177, p. 27-40 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1

Locke, J. M., Wei, F. Y., Tomizawa, K., Weedon, M. N. & Harries, L. W., Mar 6 2015, In : Diabetologia. 58, 4, p. 745-748 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A combination of YM-155, a small molecule survivin inhibitor, and IL-2 potently suppresses renal cell carcinoma in murine model

Guo, K., Huang, P., Xu, N., Xu, P., Kaku, H., Zheng, S., Xu, A., Matsuura, E., Liu, C. & Kumon, H., Jan 1 2015, In : Oncotarget. 6, 25, p. 21136-21147 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A finite difference method for elastic wave scattering by a planar crack with contacting faces

Kimoto, K. & Ichikawa, Y., Jan 1 2015, In : Wave Motion. 52, p. 120-137 18 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A new theoretical mineral dissolution rate equation for physicochemical factors

Choi, J., Ichikawa, Y., Kimoto, K. & Chae, B. G., 2015, In : Geochemical Journal. 49, 5, p. 549-557 9 p.

Research output: Contribution to journalArticle

A novel leucine zipper motif-based hybrid peptide delivers a functional peptide cargo inside cells

Hakata, Y., Tsuchiya, S., Michiue, H., Ohtsuki, T., Matsui, H., Miyazawa, M. & Kitamatsu, M., Jan 7 2015, In : Chemical Communications. 51, 2, p. 413-416 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A novel PET imaging using 64cu-labeled monoclonal antibody against mesothelin commonly expressed on cancer cells

Kobayashi, K., Sasaki, T., Takenaka, F., Yakushiji, H., Fujii, Y., Kishi, Y., Kita, S., Shen, L., Kumon, H. & Matsuura, E., Jan 1 2015, In : Journal of Immunology Research. 2015, 268172.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans

Wei, F. Y., Zhou, B., Suzuki, T., Miyata, K., Ujihara, Y., Horiguchi, H., Takahashi, N., Xie, P., Michiue, H., Fujimura, A., Kaitsuka, T., Matsui, H., Koga, Y., Mohri, S., Suzuki, T., Oike, Y. & Tomizawa, K., Mar 3 2015, In : Cell Metabolism. 21, 3, p. 428-442 15 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Cell-penetrating peptide as a means of directing the differentiation of induced-pluripotent stem cells

Kaitsuka, T. & Tomizawa, K., Nov 6 2015, In : International journal of molecular sciences. 16, 11, p. 26667-26676 10 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Positron emission tomography to elucidate pharmacokinetic differences of regioisomeric retinoid x receptor agonists

Kobayashi, T., Furusawa, Y., Yamada, S., Akehi, M., Takenaka, F., Sasaki, T., Akahoshi, A., Hanada, T., Matsuura, E., Hirano, H., Tai, A. & Kakuta, H., Mar 12 2015, In : ACS Medicinal Chemistry Letters. 6, 3, p. 334-338 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Possible role of cortactin phosphorylation by protein kinase Cα in actin-bundle formation at growth cone

Yamada, H., Kikuchi, T., Masumoto, T., Wei, F. Y., Abe, T., Takeda, T., Nishiki, T., Tomizawa, K., Watanabe, M., Matsui, H. & Takei, K., Sep 1 2015, In : Biology of the Cell. 107, 9, p. 319-330 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

7-Ketocholesteryl-9-carboxynonanoate enhances ATP binding cassette transporter A1 expression mediated by PPARγ in THP-1 macrophages

Chi, Y., Wang, L., Liu, Y., Ma, Y., Wang, R., Han, X., Qiao, H., Lin, J., Matsuura, E., Liu, S. & Liu, Q., Jun 2014, In : Atherosclerosis. 234, 2, p. 461-468 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A Cancer Stem Cell Model: An Insight into the Conversion of Induced Pluripotent Stem Cells to Cancer Stem-Like Cells

Mizutani, A., Chen, L., Kasai, T., Kudoh, T., Murakami, H., Fu, L. & Seno, M., Apr 14 2014, Cancer Stem Cells. Wiley Blackwell, Vol. 9781118356166. p. 79-87 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atherosclerosis in primary antiphospholipid syndrome: Summary of clinical and pathogenic evidence

Ames, P. R. J., Lopez, L. R., Matsuura, E. & Margarita, A., Feb 2014, In : Journal of Clinical and Experimental Cardiology. 5, 2

Research output: Contribution to journalReview article

1 Citation (Scopus)

Bacteria: Prospective savior in battle against cancer

Nair, N., Kasai, T. & Seno, M., Nov 1 2014, In : Anticancer research. 34, 11, p. 6289-6296 8 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Calculation of permeability of clay mineral in natural slope by using numerical analysis

Choi, J., Chae, B. G., Kawamura, K. & Ichikawa, Y., Jan 1 2014, Landslide Science for a Safer Geoenvironment: Volume 2: Methods of Landslide Studies. Springer International Publishing, p. 21-25 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Cancer stem cells converted from pluripotent stem cells and the cancerous niche

Kasai, T., Chen, L., Mizutani, A., Kudoh, T., Murakami, H., Fu, L. & Seno, M., 2014, In : Journal of Stem Cells and Regenerative Medicine. 10, 1, p. 2-7 6 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Cancer stem cells maintain a hierarchy of differentiation by creating their niche

Matsuda, S., Yan, T., Mizutani, A., Sota, T., Hiramoto, Y., Prieto-Vila, M., Chen, L., Satoh, A., Kudoh, T., Kasai, T., Murakami, H., Fu, L., Salomon, D. S. & Seno, M., Jul 1 2014, In : International Journal of Cancer. 135, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived extracellular vesicles

Yan, T., Mizutani, A., Chen, L., Takaki, M., Hiramoto, Y., Matsuda, S., Shigehiro, T., Kasai, T., Kudoh, T., Murakami, H., Masuda, J., Hendrix, M. J. C., Strizzi, L., Salomon, D. S., Fu, L. & Seno, M., Jan 1 2014, In : Journal of Cancer. 5, 7, p. 572-584 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells

El-Ghlban, S., Kasai, T., Shigehiro, T., Yin, H. X., Sekhar, S., Ida, M., Sanchez, A., Mizutani, A., Kudoh, T., Murakami, H. & Seno, M., Feb 5 2014, In : BioMed research international. 2014, 152659.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Comparison of the long-term effects on rabbit bone defects between Tetrabone® and β-tricalcium phosphate granules implantation

Choi, S., Liu, I. L., Yamamoto, K., Honnami, M., Ohba, S., Echigo, R., Sakai, T., Igawa, K., Suzuki, S., Nishimura, R., Chung, U. I., Sasaki, N. & Mochizuki, M., Dec 5 2014, In : Journal of Artificial Organs. 17, 4, p. 344-351 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ectopic calcification: Importance of common nanoparticle scaffolds containing oxidized acidic lipids

Kumon, H., Matsuura, E., Nagaoka, N., Yamamoto, T., Uehara, S., Araki, M., Matsunami, Y., Kobayashi, K. & Matsumoto, A., Feb 1 2014, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 10, 2, p. 441-450 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Efficient drug delivery of paclitaxel glycoside: A novel solubility gradient encapsulation into liposomes coupled with immunoliposomes preparation

Shigehiro, T., Kasai, T., Murakami, M., Sekhar, S. C., Tominaga, Y., Okada, M., Kudoh, T., Mizutani, A., Murakami, H., Salomon, D. S., Mikuni, K., Mandai, T., Hamada, H. & Seno, M., Sep 29 2014, In : PloS one. 9, 9, e107976.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Efficient transduction of 11 poly-arginine peptide in an ischemic lesion of mouse brain

Gotanda, Y., Wei, F. Y., Harada, H., Ohta, K., Nakamura, K. I., Tomizawa, K. & Ushijima, K., Sep 1 2014, In : Journal of Stroke and Cerebrovascular Diseases. 23, 8, p. 2023-2030 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Estimation of soil-to-plant transfer factors of radiocesium in 99 wild plant species grown in arable lands 1 year after the Fukushima 1 Nuclear Power Plant accident

Yamashita, J., Enomoto, T., Yamada, M., Ono, T., Hanafusa, T., Nagamatsu, T., Sonoda, S. & Yamamoto, Y., Jan 1 2014, In : Journal of Plant Research. 127, 1, p. 11-22 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors

Kaitsuka, T., Noguchi, H., Shiraki, N., Kubo, T., Wei, F. Y., Hakim, F., Kume, S. & Tomizawa, K., 2014, In : Stem Cells Translational Medicine. 3, 1, p. 114-127 14 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells

Hakim, F., Kaitsuka, T., Raeed, J. M., Wei, F. Y., Shiraki, N., Akagi, T., Yokota, T., Kume, S. & Tomizawa, K., Apr 4 2014, In : Journal of Biological Chemistry. 289, 14, p. 9623-9638 16 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Hydroxyapatite coating affects the Wnt signaling pathway during peri-implant healing in vivo

Thorfve, A., Lindahl, C., Xia, W., Igawa, K., Lindahl, A., Thomsen, P., Palmquist, A. & Tengvall, P., Mar 1 2014, In : Acta Biomaterialia. 10, 3, p. 1451-1462 12 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human

Zhou, B., Wei, F. Y., Kanai, N., Fujimura, A., Kaitsuka, T. & Tomizawa, Z., Sep 2014, In : Human Molecular Genetics. 23, 17, p. 4639-4650 12 p., ddu184.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Inactivation of TRPM7 kinase activity does not impair its channel function in mice

Kaitsuka, T., Katagiri, C., Beesetty, P., Nakamura, K., Hourani, S., Tomizawa, K., Kozak, J. A. & Matsushita, M., Jul 17 2014, In : Scientific reports. 4, 5718.

Research output: Contribution to journalArticle

32 Citations (Scopus)

In vitro anti-proliferative and anti-angiogenic activities of thalidomide dithiocarbamate analogs

El-Aarag, B. Y. A., Kasai, T., Zahran, M. A. H., Zakhary, N. I., Shigehiro, T., Sekhar, S. C., Agwa, H. S., Mizutani, A., Murakami, H., Kakuta, H. & Seno, M., Aug 2014, In : International Immunopharmacology. 21, 2, p. 283-292 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)