Faculty of Pharmaceutical Sciences

Research Output 1975 2020

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2020

Characterization of non-typhoidal Salmonella isolates from children with acute gastroenteritis, Kolkata, India, during 2000–2016

Jain, P., Chowdhury, G., Samajpati, S., Basak, S., Ganai, A., Samanta, S., Okamoto, K., Mukhopadhyay, A. K. & Dutta, S., Jan 1 2020, (Accepted/In press) In : Brazilian Journal of Microbiology.

Research output: Contribution to journalArticle

Gastroenteritis
Salmonella
India
Multilocus Sequence Typing
Azithromycin

Establishment and characterization of a murine mucosal mast cell culture model

Kakinoki, A., Kameo, T., Yamashita, S., Furuta, K. & Tanaka, S., Jan 1 2020, In : International journal of molecular sciences. 21, 1, 236.

Research output: Contribution to journalArticle

Open Access
Interleukin-9
interleukins
Cell culture
Mast Cells
Bone
Hypoglycemia
Japan
Retrospective Studies
Databases
Anti-Bacterial Agents

Vectorial Proton Transport Mechanism of RxR, a Phylogenetically Distinct and Thermally Stable Microbial Rhodopsin

Kojima, K., Ueta, T., Noji, T., Saito, K., Kanehara, K., Yoshizawa, S., Ishikita, H. & Sudo, Y., Dec 1 2020, In : Scientific reports. 10, 1, 282.

Research output: Contribution to journalArticle

Open Access
Microbial Rhodopsins
Rhodopsin
Protons
Proton Pumps
Schiff Bases
2019
1 Citation (Scopus)
Acorus
Rhizome
Esterases
Quality Control
Acetylcholine

3H-Imidazo[4,5-b]pyridine-6-carboxylic acid derivatives as rexinoids with reduced teratogenicity

Takamura, Y., Takahashi, M., Nishii, M., Shibahara, O., Watanabe, M., Fujihara, M. & Kakuta, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters.

Research output: Contribution to journalArticle

Retinoid X Receptors
Carboxylic Acids
Derivatives
Zebrafish
Transcription
image reconstruction
Image reconstruction
Germanium
germanium
Cameras
3 Citations (Scopus)

A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators

Needham, D. M., Yoshizawa, S., Hosaka, T., Poirier, C., Choi, C. J., Hehenberger, E., Irwin, N. A. T., Wilken, S., Yung, C. M., Bachy, C., Kurihara, R., Nakajima, Y., Kojima, K., Kimura-Someya, T., Leonard, G., Malmstrom, R. R., Mende, D. R., Olson, D. K., Sudo, Y., Sudek, S. & 7 others, Richards, T. A., DeLong, E. F., Keeling, P. J., Santoro, A. E., Shirouzu, M., Iwasaki, W. & Worden, A. Z., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 41, p. 20574-20583 10 p.

Research output: Contribution to journalArticle

Open Access
Rhodopsin
Mimiviridae
Oceans and Seas
Phycodnaviridae
Choanoflagellata

Altered Integrative and Conjugative Elements (ICEs) in Recent Vibrio cholerae O1 Isolated From Cholera Cases, Kolkata, India

Sarkar, A., Morita, D., Ghosh, A., Chowdhury, G., Mukhopadhyay, A. K., Okamoto, K. & Ramamurthy, T., Sep 6 2019, In : Frontiers in Microbiology. 10, 2072.

Research output: Contribution to journalArticle

Open Access
Vibrio cholerae O1
Vibrio cholerae
Cholera
India
Sulfamethoxazole Drug Combination Trimethoprim
2 Citations (Scopus)

A partial agonist for retinoid X receptor mitigates experimental colitis

Masayoshi, O., Masaki, W., Narumi, I., Koichiro, S., Kei, T., Masato, H., Takahiro, Y., Aiko, E., Osamu, S., Midori, N., Michiko, F., Makoto, M., Daisuke, T., Yukihiro, F., Kakuta, H. & Koji, H., Feb 19 2019, In : International Immunology. 31, 4, p. 251-262 12 p.

Research output: Contribution to journalArticle

Retinoid X Receptors
Colitis
Cytoplasmic and Nuclear Receptors
Ulcerative Colitis
Peroxisome Proliferator-Activated Receptors

Applicability of amino acid derivative reactivity assay for prediction of skin sensitization by combining multiple alternative methods to evaluate key events

Yamamoto, Y., Fujita, M., Wanibuchi, S., Sato, A., Akimoto, M., Katsuoka, Y., Ono, A. & Kasahara, T., Jan 1 2019, In : The Journal of toxicological sciences. 44, 9, p. 585-600 16 p.

Research output: Contribution to journalArticle

Open Access
Assays
Skin
Derivatives
Amino Acids
Acids

Application of High-Sensitivity UV photoemission Spectroscopy to Examine the Electronic Structure of Thermophilic Rhodopsin

Sano, D., Ide, I., Akiyama, T., Tanaka, Y., Sudo, Y., Murata, T. & Ishii, H., Jul 3 2019, In : Molecular Crystals and Liquid Crystals. 687, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

Rhodopsin
Photoelectron spectroscopy
Ultraviolet spectroscopy
Electronic structure
photoelectric emission
2 Citations (Scopus)

A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation

Morichika, D., Miyahara, N., Fujii, U., Taniguchi, A., Oda, N., Senoo, S., Kataoka, M., Tanimoto, M., Kakuta, H., Kiura, K., Maeda, Y. & Kanehiro, A., Jan 3 2019, In : Respiratory Research. 20, 1, 2.

Research output: Contribution to journalArticle

Retinoid X Receptors
Pulmonary Emphysema
Emphysema
Inflammation
Pancreatic Elastase
1 Citation (Scopus)

Association between rapid antigen detection tests and antibiotics for acute pharyngitis in Japan: A retrospective observational study

Teratani, Y., Hagiya, H., Koyama, T., Ohshima, A., Zamami, Y., Tatebe, Y., Tasaka, K., Shinomiya, K., Kitamura, Y., Sendo, T., Hinotsu, S. & Kano, M. R., Jan 1 2019, (Accepted/In press) In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Pharyngitis
Observational Studies
Japan
Retrospective Studies
Anti-Bacterial Agents
5 Citations (Scopus)

Attenuation of Macrophage Migration Inhibitory Factor-Stimulated Signaling via S-Nitrosylation

Nakahara, K., Fujikawa, K., Hiraoka, H., Miyazaki, I., Asanuma, M., Ito, A., Takasugi, N. & Uehara, T., Jan 1 2019, In : Biological & pharmaceutical bulletin. 42, 6, p. 1044-1047 4 p.

Research output: Contribution to journalArticle

Open Access
Macrophage Migration-Inhibitory Factors
Brain-Derived Neurotrophic Factor
p38 Mitogen-Activated Protein Kinases
Nitric Oxide Donors
Post Translational Protein Processing

Chloroethylating anticancer drug-induced mutagenesis and its repair in Escherichia coli

Yamada, Y., Watanabe, S., Okamoto, K., Arimoto, S., Takahashi, E., Negishi, K. & Negishi, T., Apr 5 2019, In : Genes and Environment. 41, 1, 11.

Research output: Contribution to journalArticle

Open Access
Nimustine
Mutagenesis
DNA Repair
Carmustine
repair

Clinical pharmacokinetics of oral azithromycin in epididymal tissue

Sadahira, T., Wada, K., Ikawa, K., Morikawa, N., Mitsui, M., Araki, M., Fujiyoshi, M., Ishii, A., Watanabe, M., Watanabe, T. & Nasu, Y., Jan 1 2019, In : Journal of Infection and Chemotherapy.

Research output: Contribution to journalArticle

Azithromycin
Pharmacokinetics
Epididymitis
Chlamydia trachomatis
Orchiectomy
1 Citation (Scopus)
Vibrio cholerae
Resuscitation
Proteomics
Temperature
Proteins

Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening

Yamada, S., Kawasaki, M., Fujihara, M., Watanabe, M., Takamura, Y., Takioku, M., Nishioka, H., Takeuchi, Y., Makishima, M., Motoyama, T., Ito, S., Tokiwa, H., Nakano, S. & Kakuta, H., Oct 10 2019, In : Journal of Medicinal Chemistry. 62, 19, p. 8809-8818 10 p.

Research output: Contribution to journalArticle

7-hydroxycoumarin
Retinoid X Receptors
Competitive Binding
Fluorescence
Ligands

Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors

Izumi-Nakaseko, H., Fujiyoshi, M., Hagiwara-Nagasawa, M., Goto, A., Chiba, K., Kambayashi, R., Naito, A. T., Ando, K., Kanda, Y., Ishii, I. & Sugiyama, A., Jan 1 2019, In : Cardiovascular Toxicology.

Research output: Contribution to journalArticle

Left Ventricular Function
Protein-Tyrosine Kinases
Induced Pluripotent Stem Cells
Dogs
Stem cells
Open Access
Fluorescence
Xanthenes
Water
Nitrogen

Differential scanning fluorimetric analysis of the amino-acid binding to taste receptor using a model receptor protein, the ligand-binding domain of fish T1r2a/T1r3

Yoshida, T., Yasui, N., Kusakabe, Y., Ito, C., Akamatsu, M. & Yamashita, A., Jan 1 2019, In : PloS one. 14, 10, e0218909.

Research output: Contribution to journalArticle

Open Access
fluorometry
Protein Binding
Fish
Fishes
Fluorometry

Effect of CYP3A5*3 genetic variant on the metabolism of direct-acting antivirals in vitro: a different effect on asunaprevir versus daclatasvir and beclabuvir

Matsumoto, J., San, S. N., Fujiyoshi, M., Kawauchi, A., Chiba, N., Tagai, R., Sanbe, R., Yanaka, S., Sakaue, H., Kato, Y., Nakamura, H., Yamada, H. & Ariyoshi, N., Jan 1 2019, (Accepted/In press) In : Journal of Human Genetics.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Antiviral Agents
8-cyclohexyl-N-((dimethylamino)sulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-((3-methyl-3,8-diazabicyclo(3.2.1)oct-8-yl)carbonyl)cycloprop(d)indolo(2,1-a)(2)benzazepine-5-carboxamide
In Vitro Techniques
BMS-790052

Effects of dexamethasone to reverse decreased hepatic midazolam metabolism in rats with acute renal failure

Doi, M., Kajikawa, N. & Aiba, T., Jan 1 2019, (Accepted/In press) In : Xenobiotica.

Research output: Contribution to journalArticle

Midazolam
Acute Kidney Injury
Metabolism
Dexamethasone
Rats

Efficient and practical synthesis of N-acetyl enamides from ketoximes by unique iron catalytic system

Kunishige, T. & Sawada, D., Jun 13 2019, In : Tetrahedron Letters. 60, 24, p. 1562-1565 4 p.

Research output: Contribution to journalArticle

Oximes
Iron
Substrates

Epidemiological study on the relationship between toxin production and psm-mec mutations in MRSA isolates in Thailand

Tabuchi, F., Lulitanond, A., Lulitanond, V., Thunyaharn, S. & Kaito, C., Jan 1 2019, (Accepted/In press) In : MICROBIOLOGY and IMMUNOLOGY.

Research output: Contribution to journalArticle

Thailand
Methicillin-Resistant Staphylococcus aureus
Epidemiologic Studies
Chromosomes
Mutation

Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate-induced renal damage in rats via antioxidant, anti-inflammatory, and antiapoptotic actions

Abouelela, M. E., Orabi, M. A. A., Abdelhamid, R. A., Abdelkader, M. S., Madkor, H. R., Darwish, F. M. M., Hatano, T. & Elsadek, B. E. M., Jan 1 2019, (Accepted/In press) In : Journal of Traditional and Complementary Medicine.

Research output: Contribution to journalArticle

Open Access
Ceiba
Methotrexate
Anti-Inflammatory Agents
Antioxidants
Kidney

Fall-related mortality trends in older Japanese adults aged ≥65 years: A nationwide observational study

Hagiya, H., Koyama, T., Zamami, Y., Tatebe, Y., Funahashi, T., Shinomiya, K., Kitamura, Y., Hinotsu, S., Sendo, T., Rakugi, H. & Kano, M. R., Dec 11 2019, In : BMJ Open. 9, 12, e033462.

Research output: Contribution to journalArticle

Open Access
Observational Studies
Mortality
Population
Japan
Public Health

Fluorine-18 (18F)-labeled retinoid x receptor (RXR) partial agonist whose tissue transferability is affected by other RXR ligands

Takamura, Y., Shibahara, O., Watanabe, M., Fujihara, M., Yamada, S., Akehi, M., Sasaki, T., Hirano, H. & Kakuta, H., Jan 1 2019, In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Positron emission tomography
Fluorine
Positron-Emission Tomography
Tissue
Ligands

Function of essential chloride and arginine residue in nucleotide binding to vesicular nucleotide transporter

Iwai, Y., Kamatani, S., Moriyama, S. & Omote, H., Jun 1 2019, In : Journal of biochemistry. 165, 6, p. 479-486 8 p.

Research output: Contribution to journalArticle

Arginine
Chlorides
Nucleotides
Adenosine Triphosphate
Vesicular Glutamate Transport Proteins
5 Citations (Scopus)

GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice

Chowdhury, S., Matsubara, T., Miyazaki, T., Ono, D., Fukatsu, N., Abe, M., Sakimura, K., Sudo, Y. & Yamanaka, A., Jun 4 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
GABAergic Neurons
Ventral Tegmental Area
Eye movements
Eye Movements
gamma-Aminobutyric Acid

Genomic and biological features of Plasmodium falciparum resistance against antimalarial endoperoxide N-89

Morita, M., Hayashi, K., Sato, A., Hiramoto, A., Kaneko, O., Isogawa, R., Kurosaki, Y., Miyoshi, S., Chang, K. S., Wataya, Y. & Kim, H-S., Oct 20 2019, In : Gene. 716, 144016.

Research output: Contribution to journalArticle

Antimalarials
Plasmodium falciparum
Clone Cells
Drug Resistance
Genes

Identification of 2H phosphoesterase superfamily proteins with 2′-CPDase activity

Mitsutomi, S., Akimitsu, N., Sekimizu, K. & Kaito, C., Oct 2019, In : Biochimie. 165, p. 235-244 10 p.

Research output: Contribution to journalArticle

Proteins
Cyclic Nucleotides
Ligases
RNA
Bacilli

Identification of the minimal region of peptide derived from ADP-ribosylation factor1 (ARF1) that inhibits IgE-mediated mast cell activation

Uchida, R., Egawa, T., Fujita, Y., Furuta, K., Taguchi, H., Tanaka, S. & Nishida, K., Jan 1 2019, In : Molecular Immunology. 105, p. 32-37 6 p.

Research output: Contribution to journalArticle

Mast Cells
Adenosine Diphosphate
Immunoglobulin E
Peptides
Cell Degranulation
5 Citations (Scopus)

In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers

Watanabe, S., Hayashi, K., Toh, K., Kim, H. J., Liu, X., Chaya, H., Fukushima, S., Katsushima, K., Kondo, Y., Uchida, S., Ogura, S., Nomoto, T., Takemoto, H., Cabral, H., Kinoh, H., Tanaka, H., Kano, M., Matsumoto, Y., Fukuhara, H., Uchida, S. & 5 others, Nangaku, M., Osada, K., Nishiyama, N., Miyata, K. & Kataoka, K., Apr 24 2019, In : Nature communications. 10, 1, p. 1894 1894.

Research output: Contribution to journalArticle

Open Access
rendezvous
oligonucleotides
nucleic acids
Oligonucleotides
Nucleic Acids

In vivo study on mechanism underlying increased pharmacological effects of phenobarbital in rats with glycerol-induced acute renal failure

Okada, A., Suzuki, K., Hara, K., Kojina, M. & Aiba, T., Jan 1 2019, In : Biological and Pharmaceutical Bulletin. 42, 3, p. 501-506 6 p.

Research output: Contribution to journalArticle

Open Access
Phenobarbital
Acute Kidney Injury
Glycerol
Pharmacology
GABA-A Receptors

Isolation and identification of photoproducts from UVA-irradiated mixture of N-nitrosoproline with 2'-deoxyadenosine

Aoyama, S., Asahi, C., Sano, K., Kimura, S., Suzuki, T., Hatano, T. & Arimoto, S., May 15 2019, In : Journal of Photochemistry and Photobiology A: Chemistry. 377, p. 159-166 8 p.

Research output: Contribution to journalArticle

isolation
Irradiation
saturation
irradiation
Saturation (materials composition)
5 Citations (Scopus)

MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER–mitochondria contact sites

Takeda, K., Nagashima, S., Shiiba, I., Uda, A., Tokuyama, T., Ito, N., Fukuda, T., Matsushita, N., Ishido, S., Iwawaki, T., Uehara, T., Inatome, R. & Yanagi, S., Jan 1 2019, In : EMBO Journal. e100999.

Research output: Contribution to journalArticle

Open Access
Endoplasmic Reticulum Stress
Ubiquitination
Apoptosis
Mitochondria
Oligomerization

Modified dehydroellagitannins from Davidia involucrata leaves

Esumi, A., Aoyama, H., Shimozu, Y., Taniguchi, S. & Hatano, T., Jan 1 2019, In : Heterocycles. 98, 7, p. 895-903 9 p.

Research output: Contribution to journalArticle

Open Access
Nyssaceae
Hydrolyzable Tannins
Acids
China
granatin B

Oral activity of the antimalarial endoperoxide 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) against Leishmania donovani complex

Kwofie, K. D., Sato, K., Sanjoba, C., Hino, A., Shimogawara, R., Amoa-Bosompem, M., Ayi, I., Boakye, D. A., Anang, A. K., Chang, K. S., Ohashi, M., Kim, H-S., Ohta, N., Matsumoto, Y. & Iwanaga, S., Mar 1 2019, In : PLoS neglected tropical diseases. 13, 3, p. e0007235

Research output: Contribution to journalArticle

Open Access
Leishmania donovani
Visceral Leishmaniasis
Antimalarials
miltefosine
Pharmaceutical Preparations

Oral anticoagulants usage in Japanese patients aged 18-74 years with non-valvular atrial fibrillation: a retrospective analysis based on insurance claims data

Ohshima, A., Koyama, T., Ogawa, A., Zamami, Y., Tanaka, H. Y., Kitamura, Y., Sendo, T., Hinotsu, S., Miller, M. W. & Kano, M. R., Nov 18 2019, In : Family practice. 36, 6, p. 685-692 8 p.

Research output: Contribution to journalArticle

Insurance
Anticoagulants
Atrial Fibrillation
Warfarin
Embolism
4 Citations (Scopus)

Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness

Tanaka, H., Kitahara, K., Sasaki, N., Nakao, N., Sato, K., Narita, H., Shimoda, H., Matsusaki, M., Nishihara, H., Masamune, A. & Kano, M., Feb 1 2019, In : Biomaterials. 192, p. 355-367 13 p.

Research output: Contribution to journalArticle

Pancreatic Stellate Cells
Pancreatic Neoplasms
Extracellular Matrix
Cysteine
Tissue
2 Citations (Scopus)

Pattern of antibiotic prescriptions for outpatients with acute respiratory tract infections in Japan, 2013-15: a retrospective observational study

Teratani, Y., Hagiya, H., Koyama, T., Adachi, M., Ohshima, A., Zamami, Y., Tanaka, H. Y., Tatebe, Y., Tasaka, K., Mikami, N., Shinomiya, K., Kitamura, Y., Kano, M. R., Hinotsu, S. & Sendo, T., Jul 31 2019, In : Family practice. 36, 4, p. 402-409 8 p.

Research output: Contribution to journalArticle

Respiratory Tract Infections
Observational Studies
Prescriptions
Japan
Outpatients

Pharmacokinetic analysis of new synthetic antimalarial N-251

Okada, K., Sato, A., Hiramoto, A., Isogawa, R., Kurosaki, Y., Higaki, K., Miyoshi, S., Chang, K. S. & Kim, H-S., Jul 5 2019, In : Tropical Medicine and Health. 47, 1, 40.

Research output: Contribution to journalArticle

Open Access
Antimalarials
Pharmacokinetics
Oral Administration
Parasites
Area Under Curve
2 Citations (Scopus)
Eubacterium
Rhodopsin
Microbial Rhodopsins
Ocular Adaptation
Sunlight

Place of death trends among patients with dementia in Japan: a population-based observational study

Koyama, T., Sasaki, M., Hagiya, H., Zamami, Y., Funahashi, T., Ohshima, A., Tatebe, Y., Mikami, N., Shinomiya, K., Kitamura, Y., Sendo, T., Hinotsu, S. & Kano, M. R., Dec 1 2019, In : Scientific reports. 9, 1, 20235.

Research output: Contribution to journalArticle

Open Access
Observational Studies
Dementia
Japan
Population
Nursing Homes
Open Access
Industry
Intellectual Property
Drug Industry
Drug Discovery
Pharmaceutical Preparations
1 Citation (Scopus)

Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination

Yamanashi, T., Maki, M., Kojima, K., Shibukawa, A., Tsukamoto, T., Chowdhury, S., Yamanaka, A., Takagi, S. & Sudo, Y., Dec 1 2019, In : Scientific reports. 9, 1, 7863.

Research output: Contribution to journalArticle

Open Access
Caenorhabditis elegans
Lighting
Anions
Light
Ion Pumps
1 Citation (Scopus)

Retinal-Salinixanthin Interactions in a Thermophilic Rhodopsin

Misra, R., Eliash, T., Sudo, Y. & Sheves, M., Oct 1 2019, In : Journal of Physical Chemistry B. 123, 1, p. 10-20 11 p.

Research output: Contribution to journalArticle

Retinaldehyde
Rhodopsin
Dichroism
Chromophores
Circular dichroism spectroscopy